Journal of the American Chemical Society, 135(3), 1102-1109 (2012-12-13)
Simultaneous monitoring of multiple molecular interactions and multiplexed detection of several diagnostic biomarkers at very low concentrations have become important issues in advanced biological and chemical sensing. Here we present an optically multiplexed six-color Förster resonance energy transfer (FRET) biosensor
Dalton transactions (Cambridge, England : 2003), 42(6), 2224-2231 (2012-12-01)
In this paper fluorescent magnetic Fe(3)O(4)@m-SiO(2)@YPO(4):Tb(3+) particles with a size of 52 nm have been prepared and characterized. The surface of the nanoparticles was modified with β-cyclodextrin and folic acid using glutathione as a linker. The hydrophobic anticancer drug 5-fluorouracil
One of the greatest challenges in cancer therapy is to develop methods to deliver chemotherapy agents to tumor cells while reducing systemic toxicity to noncancerous cells. A promising approach to localizing drug release is to employ drug-loaded nanoparticles with coatings
Human phospholipid scramblase 1 (hPLSCR1) belongs to the ATP-independent class of phospholipid translocators which possess a single EF-hand-like Ca(2+)-binding motif and also a C-terminal helix (CTH). The CTH domain of hPLSCR1 was believed to be a putative single transmembrane helix
Journal of the American Chemical Society, 135(10), 3812-3814 (2013-02-26)
We report the rational design of a 20-mer basic peptide, derived from the transcriptional antitermination protein N of bacteriophage P22, equipped with a luminescent DOTA[Tb(3+)] macrocyclic complex and a sensitizing tryptophan antenna. Folding of this peptide into an α helical
Rechargeable solid-state batteries are becoming increasingly important due to wide-spread use in computers, portable electronics, and vehicular applications.
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