Langmuir : the ACS journal of surfaces and colloids, 34(29), 8678-8684 (2016-04-05)
Diatoms are unicellular algae that construct cell walls called frustules by the precipitation of silica, using special proteins that order the silica into a wide variety of nanostructures. The diatom species Cylindrotheca fusiformis contains proteins called silaffins within its frustules
We have previously described the photoactivated depot (PAD) approach for the light-stimulated release of therapeutic proteins such as insulin. The aim of this method is to release insulin from a shallow dermal depot in response to blood glucose information, using
Journal of biomedical materials research. Part B, Applied biomaterials, 108(4), 1274-1280 (2019-08-21)
We recently reported a novel method to modify the polylactic acid (PLLA) nanofiber scaffold with IKVAV peptide/oligo (d-lactic acid) (ODLA) heteroconjugates. However, a part of the IKVAV sequence was not exposed to the outermost surface and therefore, cell adhesion was
International journal of molecular sciences, 20(7) (2019-04-11)
The growing integration of quality-by-design (QbD) concepts in biomanufacturing calls for a detailed and quantitative knowledge of the profile of impurities and their impact on the product safety and efficacy. Particularly valuable is the determination of the residual level of
Biotechnology and bioengineering, 117(2), 438-452 (2019-10-28)
The clearance of host cell proteins (HCPs) is of crucial importance in biomanufacturing, given their diversity in composition, structure, abundance, and occasional structural homology with the product. The current approach to HCP clearance in the manufacturing of monoclonal antibodies (mAbs)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
