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440140

Sigma-Aldrich

(3-Aminopropyl)triethoxysilane

(3-Aminopropyl)triethoxysilane

99%

Synonym(s):

3-Triethoxysilylpropylamine, APTES, APTS

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€107.00
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€370.00

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100 ML
€107.00
500 ML
€370.00

About This Item

Linear Formula:
H2N(CH2)3Si(OC2H5)3
CAS Number:
919-30-2
Molecular Weight:
221.37
Beilstein:
1754988
EC Number:
213-048-4
MDL number:
MFCD00008207
UNSPSC Code:
12352103
PubChem Substance ID:
24867571
NACRES:
NA.23

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Quality Level

200

Assay

99%

form

liquid

bp

217 °C/760 mmHg (lit.)

density

0.946 g/mL at 25 °C (lit.)

SMILES string

CCO[Si](CCCN)(OCC)OCC

InChI

1S/C9H23NO3Si/c1-4-11-14(12-5-2,13-6-3)9-7-8-10/h4-10H2,1-3H3

InChI key

WYTZZXDRDKSJID-UHFFFAOYSA-N

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General description

(3-Aminopropyl)tiethoxysilane (APTES) is used as an amino-silane which is mainly used as a dispersant. APTES attaches an amino group to the functional silane for bio-conjugation.[1][2]

Application

Forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. Used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.[3] Recently (3-Aminopropyl)triethoxysilane has been used to prepare dye-doped silica nanoparticles with minimal aggregation and minimal nonspecific binding with biomolecules.[4]
Self-assembled monolayer (SAM) of APTES can be used to improve the adhesion of graphene flakes and SiO2 to enable better contact with the metal electrodes. These electrodes may be used as electro-responsive tools for bio-sensing applications.[5] It can be used to functionalize silane diazirine for fiber optic biosensor application.[6] Hollow microcarriers (HMCs) can be surface modified with APTES which may be used for regenerative medicines and recombinant cells in biopharmaceutical industries.[7]
Used in a preparation of a series of tenary composite films of polyimide/SiO/polydiphenylsiloxane with good optical transparency.[8]

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H314,H317

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

199.4 °F - closed cup

Flash Point(C)

93 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF3340V
MKCW1275
WXBF4265V
MKCT8021
MKCT1978

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Photoinducible silane diazirine as an effective crosslinker in the construction of a chemiluminescent immunosensor targeting a model E. coli analyte.
Ye Kehan, et al
Sensors and Actuators B, Chemical, 256(1), 234-242 (2018)
Hollow microcarriers for large-scale expansion of anchorage-dependent cells in a stirred bioreactor.
YekrangSafakar, et al.
Biotechnology and Bioengineering, 115(7), 1717-1728 (2018)
Functionalisation of Detonation Nanodiamond for Monodispersed, Soluble DNA-Nanodiamond Conjugates Using Mixed Silane Bead-Assisted Sonication Disintegration.
Edgington, et al.
Scientific Reports, 8(1), 728-728 (2018)
Polymer International, 55, 1277-1277 (2006)
Platinum nanoparticles homogenously decorating multilayered reduced graphene oxide for electrical nanobiosensor applications.
Proa-Coronado, et al.
Thin Solid Films, 658(1), 54-60 (2018)
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Articles

Functionalized Graphene Oxide: Properties & Applications

Professor Aran discusses engineering graphene-based materials through careful functionalization, enabling diverse applications.

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Questions

1–10 of 11 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Bonjour, Comment pouvons nous prélever l'APTES sans détériorer le produit?

    1 answer

    1. 440140 is a neat material of (3-Aminopropyl)triethoxysilane (APTES). As per Section 7 of SDS: https://www.sigmaaldrich.com/sds/aldrich/440140?userType=anonymous, it is recommended to handle the material in inert gas environment.

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  4. what is the minimum coverage of this silane (m2/g)?

    1 answer

    1. Unfortunately, there is no information on the minimum coverage of this material. It would depend on the coating method, including solvent, temperature, etc.

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  5. Can this product be used to silanize a surface by using silane deposition via gas-phase evaporation?

    1 answer

    1. This material has not been tested for use in silane deposition. APTES is referenced in the literature frequently in the vapor phase deposition of biosensors. The suitability would have to be determined experimentally.
      Please see the links below to review examples of this process:
      https://www.mdpi.com/2079-6374/13/1/36
      https://pubs.acs.org/doi/10.1021/acs.langmuir.8b01044

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  6. Does this solution have an expiry date?

    1 answer

    1. This product is assigned an expiration date of 2 years from the quality release date. Expiration dates are lot specific and printed on the label as well as the Certificate of Analysis. Please see the link below to review a sample Certificate of Analysis: https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/440140-BULKMKCT8021.pdf

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  7. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  8. What is the refractive index of Product 440140, APTES (3-Aminopropyl)triethoxysilane)?

    1 answer

    1. According to our supplier the refractive index is 1.420.

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  9. What is Product 440140, APTES (3-Aminopropyl)triethoxysilane) soluble in?

    1 answer

    1. This product is soluble in water.

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  10. What is the viscosity of Product 440140, APTES (3-Aminopropyl)triethoxysilane)?

    1 answer

    1. According to our supplier’s information the viscosity is 1.6 cS.

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1–10 of 11 Questions  

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