Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

425311

Sigma-Aldrich

IR-780 iodide

Dye content ≥95 %

Synonym(s):

2-[2-[2-Chloro-3-[(1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-1-propylindolium iodide

Sign Into View Organizational & Contract Pricing

Select a Size

1 G
€99.00

€99.00

Please contact Customer Service for Availability
Request a Bulk Order
All Photos(2)

Select a Size

Change View
1 G
€99.00

About This Item

Empirical Formula (Hill Notation):
C36H44ClIN2
CAS Number:
207399-07-3
Molecular Weight:
667.11
MDL number:
MFCD00191907
UNSPSC Code:
12352103
PubChem Substance ID:
24866626
NACRES:
NA.23

€99.00

Please contact Customer Service for Availability
Request a Bulk Order

form

solid

Quality Level

100

composition

Dye content, ≥95%

mp

232-234 °C (lit.)

λmax

780 nm

SMILES string

[I-].CCCN1c2ccccc2C(C)(C)/C1=C\C=C3/CCCC(\C=C\C4=[N+](CCC)c5ccccc5C4(C)C)=C3Cl

InChI

1S/C36H44ClN2.HI/c1-7-24-38-30-18-11-9-16-28(30)35(3,4)32(38)22-20-26-14-13-15-27(34(26)37)21-23-33-36(5,6)29-17-10-12-19-31(29)39(33)25-8-2;/h9-12,16-23H,7-8,13-15,24-25H2,1-6H3;1H/q+1;/p-1

InChI key

IRPKBYJYVJOQHQ-UHFFFAOYSA-M

Related Categories

General description

IR-780 iodide is a near-infrared lipophilic cation heptamethine fluorescent dye. It has a good fluorescent intensity and can be used as a photothermal therapy agent. It shows an optical absorption spectrum of 780 nm that makes it useful as a sonodynamic therapy agent for medical treatment.[1][2][3]

Application

IR-780 based dyes can be potentially used in a biomedical application and drug delivery for tumor imaging and targeted therapy.[4][5]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SHBR3451
SHBP6713
SHBN1194
SHBM2665
MKCH7139

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sentinel lymph node mapping by a near-infrared fluorescent heptamethine dye
Zhang C, et al.
Biomaterials, 31(7), 1911-1917 (2010)
Preferential accumulation of the near infrared heptamethine dye IR-780 in the mitochondria of drug-resistant lung cancer cells
Wang Y, et al.
Biomaterials, 35(13), 4116-4124 (2014)
IR-780 dye as a sonosensitizer for sonodynamic therapy of breast tumor
Li Y, et al.
Scientific Reports, 6(28), 25968-25968 (2016)
IR-780 dye for near-infrared fluorescence imaging in prostate cancer
Yi X, et al.
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 21(28), 511-511 (2015)
IR-780 dye loaded tumor targeting theranostic nanoparticles for NIR imaging and photothermal therapy
Yue C, et al.
Biomaterials, 34(28), 6853-6861 (2013)
View All Related Papers

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service