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252805

Sigma-Aldrich

DHEA

≥97% (HPLC), powder, GABAA receptor negative modulator, Calbiochem®

Synonym(s):

DHEA, Dehydro- epi-androsterone, Dehydroisoandrosterone, Prasterone, 3-Hydroxyandrost-5-en-17-one

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About This Item

Empirical Formula (Hill Notation):
C19H28O2
CAS Number:
Molecular Weight:
288.42
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.77

product name

DHEA, Major secretory steroidal product of the adrenal gland.

Quality Level

Assay

≥97% (HPLC)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

off-white

solubility

ethanol: 20 mg/mL

shipped in

ambient

storage temp.

10-30°C

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1

InChI key

FMGSKLZLMKYGDP-USOAJAOKSA-N

General description

Major secretory steroidal product of the adrenal gland. DHEA and its sulfated metabolite, DHEA-S, are negative modulators of GABAA receptors.
Major secretory steroidal product of the adrenal gland. DHEA, and its sulfated metobolite DHEA-S, are negative modulators of GABAA receptors.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Negative modulators of GABAA receptors
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Other Notes

Hansen, S.L., et al. 1999. Mol. Pharmacol. 55, 489.
Imamura, M., and Prasad, C. 1998. Biochem. Biophys. Res. Commun.243, 771.
Majewska, M.D., et al. 1990. Brain Res.526, 143.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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