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S3547

Sigma-Aldrich

Sesame oil

Antioxidant, delivery vehicle for fat-soluble compounds

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

Sesamum indicum (sesame)

Quality Level

form

liquid

density

0.92 g/mL at 25 °C

functional group

oleic acid

lipid type

oils

shipped in

ambient

storage temp.

room temp

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General description

Sesame oil may be used in the production of biodiesel and may serve as a viable alternative for the diesel fuel. It acts as an antioxidant having neuroprotective activity on brain hippocampus of rat in focal cerebral ischemia, when given as a dietary supplement. Consumption of sesame oil has a beneficial effect on blood glucose, glycosylated hemoglobin, lipid peroxidation, and antioxidant levels in diabetic rats.

Application

Sesame oil is suitable:
  • for dissolving free testosterone
  • for the preparation of tamoxifen i.p. injection
  • for dissolving aromatizable androgen testosterone and non-aromatizable androgen 5α-dihydrotestosterone
  • as a delivery vehicle for the injection of estradiol benzoate
  • for dissolving progesterone and estradiol-17β
  • for dissolving semisynthetic form of acetyl-11-keto-β-boswellic acid
Used in research applications as delivery vehicle for fat-soluble compounds including steroidal hormones and toxins. Sesame oil has antioxidant properties and was shown to protect against lipopolysaccharide (LPS)-stimulated oxidative stress in animal models.

Storage Class Code

10 - Combustible liquids

WGK

awg

Flash Point(F)

491.0 °F

Flash Point(C)

255 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Saif Ahmad et al.
Life sciences, 79(20), 1921-1928 (2006-07-11)
Oxidative stress may be regarded as an imbalance between free radical production and opposing antioxidant defenses. Free radical oxidative stress is implicated in rat cerebral ischemia and naturaceutical antioxidants are dietary supplements that have been reported to have neuroprotective activity.
Abdurrahman Saydut et al.
Bioresource technology, 99(14), 6656-6660 (2008-01-08)
The sesame (Sesamum indicum L.) oil was extracted from the seeds of the sesame that grows in Diyarbakir, SE Anatolia of Turkey. Sesame seed oil was obtained in 58wt/wt%, by traditional solvent extraction. The methylester of sesame (Sesamum indicum L.)
Martin Höhne et al.
The American journal of pathology, 182(2), 332-338 (2012-12-19)
Podocytes, the visceral epithelial cells of the kidney glomerulus, elaborate primary and interdigitating secondary extensions to enwrap the glomerular capillaries. A hallmark of podocyte injury is the loss of unique ultrastructure and simplification of the cell shape, called foot process
Eric W Prouty et al.
The European journal of neuroscience, 50(1), 1712-1726 (2019-01-29)
Glucocorticoid hormones and serotonin (5-HT) are strongly associated with the development and treatment of depression, respectively. Glucocorticoids regulate the function of serotonergic neurons in the dorsal raphe nucleus (DR), which are the major source of 5-HT to the forebrain. DR
Justin T Hsieh et al.
Neuroendocrinology, 103(5), 518-530 (2015-09-12)
Preclinical evidence suggests that progesterone improves recovery after intracerebral hemorrhage (ICH); however, gonadal hormones have sex-specific effects. Therefore, an experimental model of ICH was used to assess recovery after progesterone administration in male and female rats. ICH was induced in

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