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905

Sigma-Aldrich

Naphthol AS-D Chloroacetate

Synonym(s):

Naphthol AS-D chloroacetate, 3-Hydroxy-2-naphthoic-o-toluidide chloroacetate

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About This Item

Empirical Formula (Hill Notation):
C20H16ClNO3
CAS Number:
35245-26-2
Molecular Weight:
353.80
EC Number:
252-463-5
MDL number:
MFCD00042714
UNSPSC Code:
12352204
PubChem Substance ID:
329769916
NACRES:
NA.47

form

powder

Quality Level

500

IVD

for in vitro diagnostic use

application(s)

hematology
histology

shipped in

dry ice

storage temp.

−20°C

SMILES string

Cc1ccccc1NC(=O)c2cc3ccccc3cc2OC(=O)CCl

InChI

1S/C20H16ClNO3/c1-13-6-2-5-9-17(13)22-20(24)16-10-14-7-3-4-8-15(14)11-18(16)25-19(23)12-21/h2-11H,12H2,1H3,(H,22,24)

InChI key

FMVKYSCWHDVMGO-UHFFFAOYSA-N

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Components

Gelatin capsules contain 20 mg

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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M R Baer et al.
Cancer, 63(11), 2192-2200 (1989-06-01)
Leukemia cutis was documented by biopsy in 18 of 877 patients (2%) with acute myelogenous leukemia (AML) seen at Roswell Park Memorial Institute (Buffalo, NY) between 1969 and 1986. French-American-British (FAB) types included four M2, one M3, ten M4, and
Usefulness of naphthol-AS-D-chloroacetate esterase (NASDCAE) in the diagnosis of AML: report of a case.
D Mastrangelo et al.
Haematologica, 70(5), 428-430 (1985-09-01)
C Haskovec et al.
Neoplasma, 37(5), 565-572 (1990-01-01)
Human myeloblastic leukemia cell line ML-1 was induced to differentiate by 1 mumol/l all-trans-retinoic acid (RA) or by 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). After 4-6 days of the induction several differentiation-associated characteristics were observed: (1) Ability to stimulate respiration burst in the
Ruliang Xu et al.
Archives of pathology & laboratory medicine, 126(5), 562-566 (2002-04-18)
Placental transmogrification of the lung is a term introduced to describe a peculiar histologic pattern characterized by formation of placental villuslike structures in the lung parenchyma. It has been reported to occur in association with bullous emphysema and lipomatosis. To
U Schmidt et al.
British journal of haematology, 68(2), 175-180 (1988-02-01)
In chronic granulocytic leukaemia, hybridoid leucocytes can regularly be found. Light microscopically they contain a mixture of eosinophilic, basophilic and naphthol AS-D chloroacetate esterase-positive granules. The present study was done to clarify the ultrastructural composition of these cells. It could
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