Expression of heat shock protein A4 (HSPA4, also called Apg-2), a member of the HSP110 family, is induced by several forms of stress. The physiological and pathological functions of HSPA4 in the intestine remain to be elucidated. We assessed HSPA4
Release of lead from 80% partially replaced service lines was compared to full lead service lines using harvested-stabilized lead pipes and field brass connectors. After more than a year of stabilization, lead release was consistent with field samples. Over the
Reverse osmosis concentrate from wastewater reclamation contains biorefractory trace organic contaminants that may pose environmental or health hazard. Due to its high conductivity, electrochemical oxidation of brine requires low voltage which is energetically favourable. However, the presence of chloride ions
Bacteria play a role in the onset and perpetuation of intestinal inflammation in IBD. Compositional alterations may also change the metabolic capacities of the gut bacteria. To examine the metabolic activity of the microbiota of patients with Crohn's disease (CD)
Nature reviews. Drug discovery, 13(12), 904-927 (2014-11-08)
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that form a family of 24 members in mammals. Evidence of the pathological roles of MMPs in various diseases, combined with their druggability, has made them attractive therapeutic targets. Initial drug discovery efforts focused
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