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Merck

S3388

Sigma-Aldrich

Sulforhodamine 101 acid chloride

Technical grade

Sinónimos:

Sulforhodamine 101 sulfonyl chloride

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About This Item

Fórmula empírica (notación de Hill):
C31H29ClN2O6S2
Número de CAS:
Peso molecular:
625.15
Beilstein/REAXYS Number:
8667894
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

form

powder

composition

Dye content, ~75%

impurities

~1 mol/mol chloroform as solvent of crystallization

solubility

methanol: 10 mg/mL

fluorescence

λex 586 nm; λem 605 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

[O-]S(=O)(=O)c1cc(ccc1C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)S(Cl)(=O)=O

InChI

1S/C31H29ClN2O6S2/c32-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-33-13-3-7-22(28(18)33)30(24)40-31-23-8-4-14-34-12-2-6-19(29(23)34)16-25(27)31/h9-10,15-17H,1-8,11-14H2

InChI key

MPLHNVLQVRSVEE-UHFFFAOYSA-N

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General description

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine. The dye can be specifically used as a marker of astroglia in the neocortex. It is commonly used for brain imaging. Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.

Application

Sulforhodamine 101 acid chloride has been used in an encapsulated fluorescent probe as a model drug to study drug-delivery properties of rhamnogalacturonan-I based microcapsules. It has also been used in confocal imaging as an astrocyte specific dye.

Linkage

Mixture of the two monosulfonyl chloride derivatives of sulforhodamine 101.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Sara Seabrooke et al.
The Journal of experimental biology, 215(Pt 17), 2945-2949 (2012-08-10)
We describe a method for calculating rates of fluorochrome transport from unstirred layer (USL) concentration gradients measured using confocal microscopy. Isolated Malpighian tubules or guts of Drosophila melanogaster were secured to depression slides and bathed in saline containing a fluorescent
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo.
Nimmerjahn A
Nature Materials, 1(1), 31-37 (2004)
In vivo imaging of oligodendrocytes with sulforhodamine 101
Robert A Hill
Nature Medicine, 11(11), 1081-1082 (2014)

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