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Merck

S7635

Sulforhodamine 101

Dye content ~95 %, Powder

Sinónimos:

SR101; 2-(3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaen-16-yl)-5-sulfobenzenesulfonate

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S7635-50MG

MXP 2,413.00

S7635-100MG

MXP 3,494.00

S7635-500MG

MXP 10,931.00

MXP 2,413.00


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Fórmula empírica (notación de Hill):
C31H30N2O7S2
Número CAS:
Peso molecular:
606.71
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
262-159-4
MDL number:
Beilstein/REAXYS Number:
3582548

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Nombre del producto

Sulforhodamine 101, Dye content ~95 %

form

powder

Quality Level

composition

Dye content, ~95%

technique(s)

microbe id | staining: suitable

color

black, dark green to brown

solubility

methanol: 1 mg/mL

ε (extinction coefficient)

≥105000 at 573-579 nm in ethanol

fluorescence

λex 586 nm; λem 605 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

OS(=O)(=O)c1ccc(C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)c(c1)S([O-])(=O)=O

InChI

1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)

InChI key

COIVODZMVVUETJ-UHFFFAOYSA-N

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1 of 4

Este artículo
230162S9012S1402
technique(s)

microbe id | staining: suitable

technique(s)

microbe id | staining: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

color

black, dark green to brown

color

brown to very dark brown, green to very dark green

color

-

color

-

fluorescence

λex 586 nm; λem 605 nm in H2O

fluorescence

-

fluorescence

-

fluorescence

λex 565 nm; λem 586 nm in H2O

solubility

methanol: 1 mg/mL

solubility

methanol: 1 mg/mL

solubility

-

solubility

methanol: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

form

powder

form

powder

form

powder

form

powder

General description

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine.

Application

Sulforhodamine 101 has been used:
  • to label astrocytes[1]
  • in quantitative polymerase chain reaction (PCR)
  • to determine the degree of disintegration in tissue sample

Biochem/physiol Actions

Sulforhodamine 101 can be specifically used as a marker of astroglia in the neocortex. It is commonly used for brain imaging. Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.[2]

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Stimulus-Evoked Calcium Transients in Somatosensory Cortex Are Temporarily Inhibited by a Nearby Microhemorrhage
Flor A
PLoS ONE (2013)
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
Nimmerjahn A, et al.
Nature Methods, 1(1), 31-31 (2004)
Jumpei Ukita et al.
Scientific reports, 9(1), 3791-3791 (2019-03-09)
A comprehensive understanding of the stimulus-response properties of individual neurons is necessary to crack the neural code of sensory cortices. However, a barrier to achieving this goal is the difficulty of analysing the nonlinearity of neuronal responses. Here, by incorporating
Danielle Tokarz et al.
PloS one, 12(10), e0186846-e0186846 (2017-10-25)
Osteocytes are the most abundant cell in the bone, and have multiple functions including mechanosensing and regulation of bone remodeling activities. Since osteocytes are embedded in the bone matrix, their inaccessibility makes in vivo studies problematic. Therefore, a non-invasive technique
David S Greenberg et al.
Nature neuroscience, 11(7), 749-751 (2008-06-17)
It is unclear how the complex spatiotemporal organization of ongoing cortical neuronal activity recorded in anesthetized animals relates to the awake animal. We therefore used two-photon population calcium imaging in awake and subsequently anesthetized rats to follow action potential firing

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