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P3655

Sigma-Aldrich

Poly-L-ornithine hydrobromide

suitable for cell culture, Mol wt 30,000-70,000

Sinónimos:

L-Ornithine homopolymer hydrobromide

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About This Item

Número de CAS:
27378-49-0
MDL number:
MFCD00237231
UNSPSC Code:
12352209
NACRES:
NA.26

product name

Poly-L-ornithine hydrobromide, mol wt 30,000-70,000

form

powder

Quality Level

200

mol wt

30,000-70,000

technique(s)

cell culture | mammalian: suitable

color

white to off-white

storage temp.

−20°C

InChI

1S/C5H12N2O2.BrH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H

InChI key

GWRQMKDBBHFVIZ-UHFFFAOYSA-N

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Application

Poly-L-ornithine hydrobromide has been used to coat coverslips in culture vessels for culturing neural progenitor cells. It has also been used to coat culture plates for culturing cerebral cells of mice.

Biochem/physiol Actions

Poly-L-ornithine is a specialized coating that acts as a charge modifier. It is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs.

Analysis Note

Molecular weight based on viscosity. Also assayed by MALLS.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Preparation and Evaluation of PEGylated Poly-L-ornithine Complex as a Novel Absorption Enhancer
Yusuke Kamiya
Biologicals : Journal of the International Association of Biological Standardization (2017)
FGF2 and Insulin Signaling Converge to Regulate Cyclin D Expression in Multipotent Neural Stem Cells
Adedamola Adepoju
Stem Cell Research (2013)
Isolation, characterization, and differentiation of multipotent neural
progenitor cells from human cerebrospinal fluid in fetal
cystic myelomeningocele
Mario Marotta
Stem Cell Research (2017)
A R Boccaccini et al.
Journal of the Royal Society, Interface, 7 Suppl 5, S581-S613 (2010-05-28)
Electrophoretic deposition (EPD) is attracting increasing attention as an effective technique for the processing of biomaterials, specifically bioactive coatings and biomedical nanostructures. The well-known advantages of EPD for the production of a wide range of microstructures and nanostructures as well
S K Tam et al.
Acta biomaterialia, 7(4), 1683-1692 (2010-12-15)
There is a need for better understanding of the biocompatibility of alginate-polycation microcapsules based on their physicochemical characteristics. Microcapsules composed of alginate with 44% (IntG) or 71% (HiG) guluronate, gelled with calcium (Ca) or barium (Ba) and coated with poly-L-lysine
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Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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