Stock solutions of item A4403, L-Ascorbic acid, can be stored at -20°C for long-term (months to years) stability.
A4403
Ácido L-ascórbico
powder, suitable for cell culture, γ-irradiated
Sinónimos:
Ácido L-treoascórbico, Factor antiescorbútico, Vitamina C
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100 MG
MXP 1,955.00
About This Item
Fórmula empírica (notación de Hill):
C6H8O6
Número de CAS:
Peso molecular:
176.12
Beilstein/REAXYS Number:
84272
EC Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.75
pH:
1.0-2.5 (25 °C, 176 g/L in water)
Productos recomendados
biological source
synthetic (organic)
Quality Level
sterility
γ-irradiated
form
powder
mol wt
Mw 176.12 g/mol
technique(s)
cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable
color
white to off-white
pH
1.0-2.5 (25 °C, 176 g/L in water)
mp
190-194 °C (dec.)
solubility
H2O: 10 mg/mL
SMILES string
OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
InChI
1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChI key
CIWBSHSKHKDKBQ-JLAZNSOCSA-N
Gene Information
human ... SLC23A2(9962)
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General description
L-ascorbic acid is an unsaturated γ-lactone ring containing an enediol configuration (–COH=COH) attached with a carbonyl group.[1]
Application
For use in cell culture applications as an antioxidant and to regenerate tocopherol.
L-ascorbic acid has been used:
L-ascorbic acid has been used:
Biochem/physiol Actions
L-ascorbic acid mainly exhibits antioxidant properties. It protects plants from oxidative stress and mammals from diseases associated with oxidative stress.[5] L-ascorbic acid mainly protects from hydroxyl radicals, superoxide and singlet oxygen. In addition, it also reduces the membrane-linked antioxidant α-tocopherol (oxidised form).[6] L-Ascorbic acid enhances endothelium-dependent vasodilation in various disorders, including diabetes, coronary artery disease, hypertension and chronic heart failure.[1]
Optional
Referencia del producto
Descripción
Precios
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Certificados de análisis (COA)
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Los clientes también vieron
R Heller et al.
The Journal of biological chemistry, 274(12), 8254-8260 (1999-03-13)
Ascorbic acid has been shown to enhance impaired endothelium-dependent vasodilation in patients with atherosclerosis by a mechanism that is thought to involve protection of nitric oxide (NO) from inactivation by free oxygen radicals. The present study in human endothelial cells
Plant L-ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing.
Davey MW
Journal of the Science of Food and Agriculture, 80, 825-860 (2000)
P L Conklin et al.
Plant physiology, 115(3), 1277-1285 (1997-12-09)
The biosynthesis of L-ascorbic acid (vitamin C) is not well understood in plants. The ozone-sensitive Arabidopsis thaliana mutant vitamin c-1 (vtc1; formerly known as soz1) is deficient in ascorbic acid, accumulating approximately 30% of wild-type levels. This deficiency could result
Xi Wang et al.
Archives of oral biology, 57(9), 1231-1240 (2012-03-30)
This study focused on the characterization of stem cells from human exfoliated deciduous teeth (SHED) in comparison with dental pulp stem cells (DPSCs) to certify SHED as a key element in tissue engineering. In the present study, SHED and DPSCs
Ying Li et al.
Protein & cell, 7(7), 478-488 (2016-06-09)
Werner syndrome (WS) is a premature aging disorder that mainly affects tissues derived from mesoderm. We have recently developed a novel human WS model using WRN-deficient human mesenchymal stem cells (MSCs). This model recapitulates many phenotypic features of WS. Based
Artículos
Importance and uses of ascorbate in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
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Protocolos
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What is the recommended storage method for stock solutions of item A4403, L-Ascorbic acid?
1 answer-
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In what solvents is A4403 soluble?
1 answer-
The product A4403 is soluble in water at a concentration of 10 mg/ml, resulting in a clear solution.
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