The product MAK106 uses linear regression fitting. The standard curve is prepared based on the donor particle concentration indicated on the label, which is batch-specific. The standard curve in table 2 is representative and for example purposes only. It's important to note that the concentrations may vary. The pmole values are calculated through dimension analysis using the amount of donor particle solution used and any subsequent dilution. For example, the most concentrated standard can be calculated by considering the volume of the donor particle. In this case, the most concentrated standard has 130 pmoles. Each subsequent dilution is two times less concentrated, resulting in concentrations of 65, 32.5, 16.25, and 8.1 pmoles.
MAK106
CETP Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Sinónimos:
Cholesteryl ester transfer protein activity assay kit
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MXP 16,408.00
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1 KIT
MXP 16,408.00
About This Item
Código UNSPSC:
12161503
NACRES:
NA.84
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uso
sufficient for 100 fluorometric tests
aplicaciones
pharmaceutical
método de detección
fluorometric
enfermedades relevantes
cardiovascular diseases
temp. de almacenamiento
2-8°C
Información sobre el gen
human ... CETP(1071)
Categorías relacionadas
Descripción general
Cholesteryl ester transfer protein (CETP) is present in normal human plasma. The protein transfers neutral lipids from high density lipoproteins (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). CETP plays an important role in lipoprotein metabolism and influences the reverse cholesterol transport pathway. The method is useful for measuring CETP activity in plasma or serum in all species that express CETP.
Aplicación
Cholesteryl ester transfer protein (CETP) activity Assay Kit has been used for measurement of CETP activity in the plasma samples.[1]
Características y beneficios
Compatible with high-throughput handling systems.
Idoneidad
Suitable for the detection of cholesteryl ester transfer protein (CETP) in plasma / serum (fresh or frozen), recombinant or purified CETP.
Principio
The CETP Activity Assay Kit uses a proprietary substrate that enables the detection of CETP-mediated transfer of neutral lipid from the substrate to a physiological acceptor. The transfer activity results in an increase in fluorescence intensity (λEx=535 nm/λEm=587 nm). In a total volume of 200 μL, the assay is linear from 0.2 to 0.8 μL of normal human plasma. Assay results not affected by endogenous plasma HDL, LDL or VLDL concentrations.
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Referencia del producto
Descripción
Precios
Código de clase de almacenamiento
10 - Combustible liquids
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The Journal of clinical endocrinology and metabolism, 105(3) (2019-10-31)
Cholesteryl ester transfer protein (CETP) regulates high-density lipoprotein (HDL) cholesterol levels and interaction between glucose, and HDL metabolism is central in the development of diabetes. We hypothesized that CETP levels would be regulated in diabetic pregnancies. We tested the hypothesis
Catherine J McNeal et al.
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We discovered that some adults with coronary heart disease (CHD) have a high density lipoprotein (HDL) subclass which induces human aortic smooth muscle cell (ASMC) apoptosis in vitro. The purpose of this investigation was to determine what properties differentiate apoptotic
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The American journal of clinical nutrition, 110(3), 617-627 (2019-06-07)
Postmenopausal women are at higher risk for cardiovascular disease (CVD) than their younger counterparts. HDL cholesterol is a biomarker for CVD risk, but the function of HDL may be more important than HDL cholesterol in deciphering disease risk. Although diet
Melissa N Martinez et al.
Journal of lipid research, 53(3), 379-389 (2012-01-05)
Mechanisms underlying changes in HDL composition caused by obesity are poorly defined, partly because mice lack expression of cholesteryl ester transfer protein (CETP), which shuttles triglyceride and cholesteryl ester between lipoproteins. Because menopause is associated with weight gain, altered glucose
Marie Cecilie Paasche Roland et al.
Scientific reports, 11(1), 6213-6213 (2021-03-20)
Cholesteryl ester transfer protein (CETP) regulates high density lipoproteins (HDL)-cholesterol (C) and HDL-C is essential for fetal development. We hypothesized that women giving birth to large-for-gestational-age (LGA) and small-for-gestational age (SGA) infants differed in longitudinal changes in lipoproteins, CETP activity
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What type of regression fitting is used for the product MAK106, and what is the method for calculating the pmoles shown in the typical standard curve in table 2?
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