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Merck

49449

Sigma-Aldrich

L-Glutamic acid

≥99.5% (NT), BioUltra

Sinónimos:

(S)-2-Aminopentanedioic acid, Glu

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About This Item

Fórmula lineal:
HO2CCH2CH2CH(NH2)CO2H
Número de CAS:
Peso molecular:
147.13
Beilstein:
1723801
Número CE:
Número MDL:
Código UNSPSC:
12352209
eCl@ss:
32160406
ID de la sustancia en PubChem:
NACRES:
NA.26
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Nombre del producto

L-Glutamic acid, BioUltra, ≥99.5% (NT)

Línea del producto

BioUltra

Nivel de calidad

Ensayo

≥99.5% (NT)

Formulario

powder

actividad óptica

[α]20/D +31.5±1.0°, c = 5% in 5 M HCl

impurezas

insoluble matter, passes filter test
≤0.5% foreign amino acids

residuo de ign.

≤0.05% (as SO4)

pérdida

≤0.05% loss on drying, 20 °C (HV)

color

white

mp

205 °C (dec.) (lit.)

solubilidad

1 M HCl: 1 M at 20 °C, clear, colorless

densidad

1.54 g/cm3 at 20 °C

trazas de anión

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

trazas de catión

Al: ≤5 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤100 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in 1 M HCl

Absorción UV

λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1

aplicaciones

cell analysis

cadena SMILES

N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

Clave InChI

WHUUTDBJXJRKMK-VKHMYHEASA-N

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Acciones bioquímicas o fisiológicas

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

Otras notas

Lesion-sparing agent, has excitotoxic properties[1]; May function as precipitating agent in protein crystallization[2]; Growth requirement of various microorganisms[3]

Aplicación

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

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Visite la Librería de documentos

Excitotoxic amino acids as neuroendocrine research tools.
J W Olney et al.
Methods in enzymology, 103, 379-393 (1983-01-01)
CRC Handbook of Microbiology, 4, 1-1 (1974)
Protein crystallization: the growth of large-scale single crystals.
G L Gilliland et al.
Methods in enzymology, 104, 370-381 (1984-01-01)
Steffen Gonda et al.
Frontiers in neuroanatomy, 14, 571351-571351 (2020-12-08)
NMDA receptors are important players for neuronal differentiation. We previously reported that antagonizing NMDA receptors with APV blocked the growth-promoting effects evoked by the overexpression of specific calcium-permeable or flip-spliced AMPA receptor subunits and of type I transmembrane AMPA receptor
Kimberly J Dougherty et al.
Neuron, 80(4), 920-933 (2013-11-26)
Locomotion is controlled by spinal networks that generate rhythm and coordinate left-right and flexor-extensor patterning. Defined populations of spinal interneurons have been linked to patterning circuits; however, neurons comprising the rhythm-generating kernel have remained elusive. Here, we identify an ipsilaterally

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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