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01905

Sigma-Aldrich

Adenosine 5′-diphosphate

≥95% (HPLC)

Sinónimos:

5′-ADP

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250 MG
MXP 2,547.00
1 G
MXP 8,096.00

MXP 2,547.00

Fecha estimada de envío29 de mayo de 2025

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250 MG
MXP 2,547.00
1 G
MXP 8,096.00

About This Item

Fórmula empírica (notación de Hill):
C10H15N5O10P2
Número de CAS:
58-64-0
Peso molecular:
427.20
Beilstein:
67722
Número CE:
200-392-5
Número MDL:
MFCD00066473
Código UNSPSC:
41106305
eCl@ss:
32160414
ID de la sustancia en PubChem:
57646699
NACRES:
NA.55

MXP 2,547.00

Fecha estimada de envío29 de mayo de 2025

Solicitar un pedido a granel

Ensayo

≥95% (HPLC)

Formulario

powder

impurezas

≤15.0% water (KFT)

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O

InChI

1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Clave InChI

XTWYTFMLZFPYCI-KQYNXXCUSA-N

Información sobre el gen

human ... HSP90AA1(3320) , P2RY1(5028)

Aplicación

Adenosine 5′-diphosphate (5′-ADP or ADP) was used as a test compound for studying the endothelium-dependent vascular response in salt sensitive (DS) and salt resistant Dahl rats (DR).[1] The product was used to study the different P2-purinergic receptor subtypes on canine vascular smooth muscle and endothelium.[2]

Acciones bioquímicas o fisiológicas

Adenosine 5′-diphosphate induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.[3]

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCM3332
BCCL7026
BCCK8317
BCCJ9038
BCCH6888

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Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

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Thomas Cuisset et al.
Journal of the American College of Cardiology, 48(7), 1339-1345 (2006-10-03)
We analyzed the benefit of a 600-mg clopidogrel loading dose on platelet reactivity and clinical outcomes after stenting for non-ST-segment elevation acute coronary syndrome (NSTE ACS). High post-treatment platelet reactivity (HPPR = adenosine diphosphate 10 mumol x l(-1) [ADP]-induced platelet
W G Mayhan
Inflammation, 16(4), 295-305 (1992-08-01)
The goal of this study was to determine the role of the synthesis and release of nitric oxide in modulating alterations in microvascular permeability of the hamster cheek pouch in response to adenosine 5'-diphosphate and bradykinin. We used intra-vital fluorescent
N J Cusack et al.
British journal of pharmacology, 76(1), 221-227 (1982-05-01)
1 Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and noncompetitively inhibits stimulated human platelet adenylate cyclase; it has been suggested that these two effects are mediated by separate ADP receptors on the platelet surface. 2 Adenosine 5'-triphosphate and seven adenine
Yoshihiro Matsumura et al.
The Journal of biological chemistry, 288(43), 31069-31079 (2013-08-31)
The C terminus of Hsp70 interacting protein (CHIP) E3 ligase functions as a key regulator of protein quality control by binding the C-terminal (M/I)EEVD peptide motif of Hsp/c70(90) with its N-terminal tetratricopeptide repeat (TPR) domain and facilitating polyubiquitination of misfolded
R N Goldberg et al.
Biophysical chemistry, 40(3), 241-261 (1991-07-01)
The thermodynamic treatment of the disproportionation reaction of adenosine 5'-diphosphate to adenosine 5'-triphosphate and adenosine 5'-monophosphate is discussed in terms of an equilibrium model which includes the effects of the multiplicity of ionic and metal bound species and the presence
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. I want a cell culture graded ADP to study endothelial functions in HUVECs. Will you guarantee that this is adequate for such study?

    1 answer

    1. This product cannot be guaranteed for this application as it is not tested for use in cell culture. A cell culture-tested version of the Adenosine 5′-diphosphate product is not currently offered.

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