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Merck

920207

Sigma-Aldrich

Cyrene γ-Valerolactone Blend

greener alternative

BioRenewable, DMF and NMP Substitute

Sinónimos:

γ-Valerolactone Cyrene solution, γ-Valerolactone solution, Cyrene solution, Cyrene γ-valerolactone solution, GVL Blend

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About This Item

Fórmula empírica (notación de Hill):
C6H8O3
Peso molecular:
128.13
UNSPSC Code:
12191502
NACRES:
NA.07

form

liquid

greener alternative product characteristics

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

renewable carbon content

100%

density

1.141 g/mL

greener alternative category

General description

Cyrene γ-Valerolactone Blend is specially formulated for use in automated processes and applications where lower viscosity is required, making it easier to handle while maintaining high yields.

This Cyrene blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene nor γ-Valerolactone have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.

This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.
We are committed to bringing you greener alternative products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is BioRenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here for more information.

Application

This cosolvent solution has been shown to have similar reaction yields to NMP and DMF for many cross-coupling reactions, such as:

Features and Benefits

  • Independently certified as 100% renewable carbon.
  • Closer physical properties of NMP and DMF while maintaining high reaction yields.
  • Sustainably produced and environmentally less hazardous than more traditional petroleum aprotic solvents
  • Both Cyrene and GVL are also much safer for handling without the genotoxic concerns of other solvents.
  • It has a lower viscosity than neat Cyrene making it more optimized for automated processes.

Legal Information

CYRENE is a trademark of Circa Group Pvt Ltd

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Referencia del producto
Descripción
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Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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Visite la Librería de documentos

Improved 2-pyridyl reductive homocoupling reaction using biorenewable solvent Cyrene?(dihydrolevoglucosenone)
Webb DA, et al.
RSC Sustainability, 1, 1522-1529 (2023)
Cyrene? blends: a greener solvent system for organic syntheses
Sullivan C, et al.
Green Chemistry, 24, 7184-7193 (2022)

Contenido relacionado

Why should you have to choose between solvents that are ecological and those that are reliable? Enjoy both at once with our biorenewable and greener solutions. Cyrene™ solvent is a new dipolar aprotic alternative to common REACH restricted solvents, such as N methyl-2-pyrrolidone (NMP) and Dimethylformamide (DMF).

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