68923

Esculetin

analytical standard

• Sinónimos: 6,7-Dihydroxycoumarin, Cichorigenin, Esculetin
• Fórmula empírica (notación de Hill): C₉H₆O₄
• Número de CAS: 305-01-1
• Peso molecular: 178.14
• Beilstein/REAXYS Number: 152788
• EC Number: 206-161-5
• MDL number: MFCD00006874
• UNSPSC Code: 12352200
• PubChem Substance ID: 329761226
• NACRES: NA.24

Propiedades

• grade: analytical standard
• Quality Level: 100
• assay: ≥97.5% (HPLC); 97.5-102.5% (NT)
• shelf life: limited shelf life, expiry date on the label
• mp: 271-273 °C (lit.)
• format: neat
• SMILES string: Oc1cc2OC(=O)C=Cc2cc1O
• InChI: 1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H
• InChI key: ILEDWLMCKZNDJK-UHFFFAOYSA-N

Descripción

General description

Esculetin is a derivative of coumarin, found in various plant species including Cichorium intybus (chicory), Bougainvillea spectabilis, Artemisia capillaris, etc and leaves of Citrus limonia (Rutaceae), Ceratostigma willmottianum, etc. It exhibits multiple pharmacological activities and is found to be a potent inhibitor of cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, catechol-O-methyl transferase, NADPH oxidase and xanthine oxidase enzymes.

Application

Esculetin may be used as an analytical reference standard for the determination of the analyte in biological and water samples by chromatography-based techniques. It may also be used as a standard in the quantification of the analyte in traditional herbal medicines by solid-phase extraction and micellar electrokinetic capillary methods, respectively.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable