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SCT070

Sigma-Aldrich

BioTracker NIM-7 Lipids and Lysosomes Live Cell Dye

Live cell imaging fluorescent probe for simultaneous dual-color tracking of lipid droplets and lysosomes

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.47

form

lyophilized

application(s)

cell analysis

detection method

fluorometric

General description

Lipid droplets (LDs) and lysosomes are specialized subunits within cells. LDs are the most hydrophobic sub-structures within cells and serve to store lipids for energy generation and membrane synthesis. Lysosomes are typically acidic organelles (pH 4.5–5.0) that play a critical role in the digestion and clearance of endocytosed and endogenous intracellular materials.BioTracker NIM-7 Lipids and Lysosomes Live Cell Dye is a naphthalimide-based fluorescent probe that allows lipid droplets and lysosomes to be labelled simultaneously and visualized separately using different excitation and detection channels. Lipid droplets and lysosomes can be visualized in the yellow and red fluorescence regions, respectively. The dye was found to have low cytotoxicity in multiple cell lines after 24 hour incubation. The dye also high photostability and can maintain 90% of original fluorescence intensity after 15 min of irradiation.Spectral properties:Lipid droplets: Excitation: 488 nm. Emission: 530-570 nm.Lysosomes: Excitation: 561 nm. Emission: 640-680 nm.Research Category:Live Cell DyeLipid Signaling

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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