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810255P

Avanti

TopFluor™ Cholesterol

Avanti Research™ - A Croda Brand

Sinónimos:

Bodipy Cholesterol; Bdp-Chol

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1 MG
MXP 6,938.00
5 MG
MXP 12,484.00
10 MG
MXP 22,593.00

MXP 6,938.00

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1 MG
MXP 6,938.00
5 MG
MXP 12,484.00
10 MG
MXP 22,593.00

About This Item

Fórmula empírica (notación de Hill):
C36H51BF2N2O
Número de CAS:
878557-19-8
Peso molecular:
576.61
Número MDL:
MFCD00066515
Código UNSPSC:
12352211
NACRES:
NA.25

MXP 6,938.00

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descripción

23-(dipyrrometheneboron difluoride)-24-norcholesterol

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 1 mg (810255P-1mg)
pkg of 1 × 10 mg (810255P-10mg)
pkg of 1 × 5 mg (810255P-5mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

Biomolecules attached to BODIPY, is readily absorbed in the visible light. It results in greater fluorescence quantum yields. It is highly photostable and less sensitive to change in polarity and pH.[1]

Aplicación

TOPFLUOR™Cholesterol is suitable:
  • for cholesterol-uptake assay[2]
  • for BODIPY cholesterol labeling in live cell experiments[3]
  • for the formation of giant Janus liposomes via poly(vinyl alcohol) (PVA)-assisted lipid swelling [4]

Acciones bioquímicas o fisiológicas

BODIPY labelled cholesterol has similar properties to that of the naïve cholesterol.[5] This serves as a cholesterol marker for live cells[1] and aids in trafficking intracellular cholesterol.[5] It might also help in indicating lipid storage diseases.[1]

Envase

5 mL Amber Glass Screw Cap Vial (810255P-10mg)
5 mL Amber Glass Screw Cap Vial (810255P-1mg)
5 mL Amber Glass Screw Cap Vial (810255P-5mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

también adquirido normalmente con este producto

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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James E Shaw et al.
Biophysical journal, 90(6), 2170-2178 (2005-12-20)
Coupling atomic force microscopy (AFM) with high-resolution fluorescence microscopy is an attractive means of identifying membrane domains by both physical topography and fluorescence. We have used this approach to study the ability of a suite of fluorescent molecules to probe
Katarina Trajkovic et al.
Science (New York, N.Y.), 319(5867), 1244-1247 (2008-03-01)
Intraluminal vesicles of multivesicular endosomes are either sorted for cargo degradation into lysosomes or secreted as exosomes into the extracellular milieu. The mechanisms underlying the sorting of membrane into the different populations of intraluminal vesicles are unknown. Here, we find
Membrane orientation and lateral diffusion of BODIPY-cholesterol as a function of probe structure
Solanko LM, et al.
Biophysical Journal, 105(9), 2082-2092 (2013)
Jameson T Crowley et al.
PLoS pathogens, 9(1), e1003109-e1003109 (2013-01-18)
Borrelia burgdorferi, the agent of Lyme disease, has cholesterol and cholesterol-glycolipids that are essential for bacterial fitness, are antigenic, and could be important in mediating interactions with cells of the eukaryotic host. We show that the spirochetes can acquire cholesterol
Robert M Littleton et al.
BMC complementary and alternative medicine, 12, 105-105 (2012-07-25)
Consumers are increasingly turning to plant-based complementary and alternative medicines to treat hypercholesterolemia. Many of these treatments are untested and their efficacy is unknown. This multitude of potential remedies necessitates a model system amenable to testing large numbers of organisms
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