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8.22339

Sigma-Aldrich

Phosphoryl chloride

for synthesis

Sinónimos:

Phosphoryl chloride, Phosphorus oxide trichloride, Phosphorus oxychloride

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About This Item

Número de CAS:
10025-87-3
Peso molecular:
153.33
Número MDL:
MFCD00011443
Código UNSPSC:
12352101
Número índice de la CE:
233-046-7
NACRES:
NA.22
bp:
105.3 °C/1013 hPa
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grado

for synthesis
synthesis grade

Nivel de calidad

200

presión de vapor

36 hPa ( 20 °C)

Ensayo

≥99.0% (argenometric)

Formulario

liquid

potencia

36 mg/kg LD50, oral (Rat)

dilution

(for synthesis)

pH

1.0 (25 °C, 5 g/L in H2O)

bp

105.3 °C/1013 hPa

mp

1-2 °C

densidad

1.68 g/cm3 at 20 °C (DIN 51757)

temp. de almacenamiento

2-30°C

cadena SMILES

[P](=O)(Cl)(Cl)Cl

InChI

1S/Cl3OP/c1-5(2,3)4

Clave InChI

XHXFXVLFKHQFAL-UHFFFAOYSA-N

Categorías relacionadas

Descripción general

for synthesis

Aplicación

Phosphoryl chloride is a strong Lewis acid that can be used as:
  • A phosphorylating agent for the selective phosphorylation of alcohols, amines, and thiols.[1]
  • A dehydrating agent for alcohols, amides, and cyanohydrins.[1][2]
  • A reagent to synthesize Vilsmeier reagent for Vilsmeier-Haack formylation reactions.[1]
  • A chlorinating agent for the chlorination of heterocyclic compounds.[1]
  • A reagent to prepare dihydroisoquinolines and isoquinolines by cyclization of N-β-phenylethyl amides via Bischler-Napieralski reaction.[1]

Nota de análisis

Assay (argentometric)≥ 99.0 %Density (d 20 °C/ 4 °C)1.673 - 1.677Identity (IR)passes test

Palabra de señalización

Danger

Frases de peligro

H302 - H314 - H330 - H372

Clasificaciones de peligro

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1 - STOT RE 1 Inhalation

Órganos de actuación

Respiratory Tract

Riesgos supl.

EUH014 - EUH029

Código de clase de almacenamiento

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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