It is recommended to reconstitute this product in 20 mM sodium phosphate, pH 6.9, 0.45% NaCl, and 0.01% BSA at 5 mg/mL. Following reconstitution, store at 2 - 8°C up to 1 week. Stock solutions may be stored in working aliquots at -20°C for several months. Avoid repeated freeze/thaw cycles.
385931
Hyaluronidase, Bovine Testes
Sinónimos:
Hyaluronidase, Bovine Testes
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About This Item
Número de CAS:
Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.54
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
conjugado
conjugate (Glucosaminoglycan)
Nivel de calidad
descripción
Merck USA index - 14, 4758
Formulario
lyophilized
actividad específica
≥2500 units/mg dry wt.
fabricante / nombre comercial
Calbiochem®
condiciones de almacenamiento
OK to freeze
Condiciones de envío
ambient
temp. de almacenamiento
−20°C
Categorías relacionadas
Descripción general
Native hyaluronidase from bovine testes. Catalyzes the hydrolysis of 1,4 linkages between N-acetylhexosamine and D-glucuronate residues in chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, and hyaluronic acid.
Native hyaluronidase from bovine testes. Hyaluronic acid degrading endoglycosidase that catalyzes the hydrolysis of 1,4 linkages between N-acetylhexosamine and D-glucuronate residues in chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, and hyaluronic acid.
Note: 1 KU = 1000 units.
Advertencia
Toxicity: Standard Handling (A)
Definición de unidad
One unit is defined as the amount of enzyme that will cause the same turbidity reduction as 1.0 unit of International Standard preparation.
Reconstitución
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 week at 4°C.
Reconstitute in 20 mM sodium phosphate, pH 6.9, 0.45% NaCl, and 0.01% BSA.
Otras notas
Lokeshwar, V.B., et al. 2002. J. Biol. Chem.277, 33654.
Humphrey, I.H. 1957. Bull. WHO16, 291.
Humphrey, I.H. 1957. Bull. WHO16, 291.
Información legal
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Resp. Sens. 1
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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J H HUMPHREY
Bulletin of the World Health Organization, 16(2), 291-294 (1957-01-01)
The International Standard for Hyaluronidase is derived from a blend of four batches of bovine testicular hyaluronidase which had been purified so as to contain approximately 400 units per milligram. The material was mixed with beta-lactose, and lyophilized. Tablets were
Vinata B Lokeshwar et al.
The Journal of biological chemistry, 277(37), 33654-33663 (2002-06-27)
Hyaluronidase is a hyaluronic acid-degrading endoglycosidase that is present in many toxins and the levels of which are elevated in cancer. Increased concentration of HYAL1-type hyaluronidase correlates with tumor progression and is a marker for grade (G) 2 or 3
Artículos
Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.
Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.
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I am doing experiments on hyaluronidase activity and I would like information on how the reconstituted enzyme performs after being frozen and thawed at both -20C and -80C
1 answer-
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What is molecular weight of this product (in kDa)?
1 answer-
The molecular weight is approximately 61 kDa. This information may be found on the Certificate of Analysis.
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We have a bottle of Hyaluronidase, Bovine Testes in our lab and need to know if it has an expiration date. The only date on the bottle is the received date written by one of the techs. If it is stored properly in the freezer what is the expiration date?
1 answer-
This product is not assigned an expiration date or recommended retest date. Customers should routinely inspect products with no expiration date or recommended retest date to ensure they perform as expected. These products are also subject to a one-year warranty from the date of shipment. For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.
To discuss further, we kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice, click on "Report Product Issues" under the Products Section with all the required information, including the lot number, so that a member of our team can reach out to you to assist further. Thank you.
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