14-607-M
PIM2 Protein, active, 25 µg
Active, human PIM2 expressed in E. coli, purified using GSH agarose, for use in Kinase Assays.
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32
Productos recomendados
biological source
human
Quality Level
mol wt
Mw 63.4 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
Gene Information
human ... PIM2(11040)
General description
Product Source: N-terminal GST-tagged recombinant full-length human PIM2
human PIM2 expressed in E. coli, purified using GSH agarose
Quality
routinely evaluated by phosphorylation of PIM2tide
Physical form
GSH agarose
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Casey J Fox et al.
Genes & development, 17(15), 1841-1854 (2003-07-19)
Growth factor withdrawal results in the termination of factor-dependent transcription. One transcript that declines rapidly following growth factor deprivation of hematopoietic cells is the serine/threonine kinase pim-2. When constitutively expressed, Pim-2 conferred long-term resistance to a variety of apoptotic stimuli
Bin Yan et al.
The Journal of biological chemistry, 278(46), 45358-45367 (2003-09-05)
Hematopoietic growth factors mediate the survival and proliferation of blood-forming cells, but the mechanisms through which these proteins produce their effects are incompletely known. Recent studies have identified the pim family of kinases as mediators of cytokine-dependent survival signals. Several
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