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07-181

Sigma-Aldrich

Anti-AMPK α-pan Antibody

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
clone:
polyclonal
application:
WB
species reactivity:
human, rat
technique(s):
western blot: suitable
citations:
18
En este momento no podemos mostrarle ni los precios ni la disponibilidad

biological source

rabbit

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... PRKAA1(5562)

Specificity

Recognizes AMP-activated protein kinase alpha subunits.

Immunogen

human AMP-activated protein a1 catalytic subunit (AEKQKHDGRVKIGHYILGD)

Application

Anti-AMPK α-pan Antibody is an antibody against AMPK α-pan for use in WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Quality

routinely evaluated by immunoblot on a rat liver protein preparation

Target description

63 kDa

Physical form

ImmunoAffinity Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

Storage and Stability

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Rat liver preparation

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Inhibition of AMP-activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53.
Kim, HS; Hwang, JT; Yun, H; Chi, SG; Lee, SJ; Kang, I; Yoon, KS; Choe, WJ; Kim, SS; Ha, J
The Journal of Biological Chemistry null
Neuroprotective Effects of AMP-Activated Protein Kinase on Scopolamine Induced Memory Impairment.
Kim, SJ; Lee, JH; Chung, HS; Song, JH; Ha, J; Bae, H
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology null
Sandra C Rodrigues et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(9), R1146-R1156 (2014-08-29)
The liver plays an essential role in maternal metabolic adaptation during late pregnancy. With regard to lipid metabolism, increased secretion of very low-density lipoprotein (VLDL) is characteristic of late pregnancy. Despite this well-described metabolic plasticity, the molecular changes underlying the
Andreas Buch Møller et al.
Journal of applied physiology (Bethesda, Md. : 1985), 118(8), 971-979 (2015-02-14)
Data from transgenic animal models suggest that exercise-induced autophagy is critical for adaptation to physical training, and that Unc-51 like kinase-1 (ULK1) serves as an important regulator of autophagy. Phosphorylation of ULK1 at Ser(555) stimulates autophagy, whereas phosphorylation at Ser(757)
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.
Lin, J; Wu, PH; Tarr, PT; Lindenberg, KS; St-Pierre, J; Zhang, CY; Mootha, VK; Jager et al.
Cell null

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