C-158

Cetirizine dihydrochloride solution

1.0 mg/mL in acetonitrile: water (9:1) (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): C₂₁H₂₅ClN₂O₃ · 2HCl
• Número de CAS: 83881-52-1
• Peso molecular: 461.81
• MDL number: MFCD00941428
• UNSPSC Code: 41116107
• PubChem Substance ID: 329774897
• NACRES: NA.24

Propiedades

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in acetonitrile: water (9:1) (as free base)
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• format: single component solution
• storage temp.: −20°C
• InChI: 1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H
• InChI key: PGLIUCLTXOYQMV-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Descripción

General description

Cetirizine is a major metabolite of the first generation antihistamine hydroxyzine. Cetirizine is also a second generation antihistamine that is sold under the trade name Zyrtec^®. This Certified Spiking Solution^® is suitable for use in a variety of GC/MS or LC/MS testing applications in forensic toxicology, urine drug testing, or clinical chemistry.

Application

• Cetirizine dihydrochloride liquid for in vitro studies: Cetirizine dihydrochloride solution is extensively utilized in in vitro biochemical assays to study histamine H1 receptor antagonism. This research is crucial for understanding the mechanisms of allergic reactions and for developing more effective antihistamine treatments (Aldawsari et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Zyrtec is a registered trademark of UCB Pharma, S.A.

Información de seguridad

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H302 + H312 + H332,H319
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 35.6 °F - closed cup
• flash_point_c: 2.0 °C - closed cup