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15879

Sigma-Aldrich

Octaethylene glycol

≥95% (oligomer purity)

Sinónimos:

PED-diol (n=8)

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About This Item

Fórmula lineal:
HO(CH2CH2O)8H
Número de CAS:
5117-19-1
Peso molecular:
370.44
EC Number:
225-856-4
MDL number:
MFCD00698694
UNSPSC Code:
12161502
PubChem Substance ID:
57647531
NACRES:
NA.22

assay

≥95% (oligomer purity)

reaction suitability

reagent type: cross-linking reagent

SMILES string

OCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C16H34O9/c17-1-3-19-5-7-21-9-11-23-13-15-25-16-14-24-12-10-22-8-6-20-4-2-18/h17-18H,1-16H2

InChI key

GLZWNFNQMJAZGY-UHFFFAOYSA-N

General description

Octaethylene glycol also known as PED-diol (n=8), is a cross linking reagent commonly used in organic synthesis.

Application

Octaethylene glycol is used as a cross-linking reagent to produce cyclic octaethylene glycol 5-nitroisophthalate. It serves as a starting material for synthesizing heterobifunctionalized clickable oligo(ethylene glycol) linkers and supramolecular polymers.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Pedro Cecílio et al.
PLoS neglected tropical diseases, 11(11), e0005951-e0005951 (2017-11-28)
The notion that previous infection by Leishmania spp. in endemic areas leads to robust anti-Leishmania immunity, supports vaccination as a potentially effective approach to prevent disease development. Nevertheless, to date there is no vaccine available for human leishmaniasis. We optimized
Efficient synthesis of diverse heterobifunctionalized clickable oligo (ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery
LN Goswami
Organic & Biomolecular Chemistry, 11, 1116-1126 (2013)
Monomers for non-bond crosslinking of vinyl polymers: II. Cyclic octaethylene glycol 5-methacrylamido-isophthalate
A Zada
European Polymer Journal, 36, 351-357 (2000)
Tamiru Negash Alkie et al.
PloS one, 13(11), e0206324-e0206324 (2018-11-02)
Mucosal vaccine delivery systems have paramount importance for the induction of mucosal antibody responses. Two studies were conducted to evaluate immunogenicity of inactivated AIV antigens encapsulated in poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles (NPs). In the first study, seven groups of specific pathogen
Jitka Neburkova et al.
Molecular pharmaceutics, 15(8), 2932-2945 (2018-02-02)
Glutamate carboxypeptidase II (GCPII) is a membrane protease overexpressed by prostate cancer cells and detected in the neovasculature of most solid tumors. Targeting GCPII with inhibitor-bearing nanoparticles can enable recognition, imaging, and delivery of treatments to cancer cells. Compared to
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