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Merck

SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

Sinónimos:
EAAT2, GLT-1
Especie:
ID UniProtKB:
ID del gen:
  • Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Número de producto
Descripción
Especie
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Especie
rat
Dihydrokainic acid, ≥98% (HPLC), powder,
Especie
rat, human
(±)-AMPA, solid,
Especie
rat
(Aminomethyl)phosphonic acid, 99%,
Especie
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Especie
rat, human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-EAAT2/SLC1A2 Antibody, clone 7K5F7, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
Dihydrokainic acid, ≥98% (HPLC), powder,
Especie
rat, human
(Aminomethyl)phosphonic acid, 99%,
Especie
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Especie
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Especie
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Especie
rat, human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human SLC1A2,
Especie
human