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Merck

GABRA2

gamma-aminobutyric acid (GABA) A receptor, alpha 2

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(2555) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14395) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
  • Rat(289606) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • cow(282236) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • chicken(770511) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • naked mole-rat(101720776) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic guinea pig(100720796) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic cat(100286789) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Domestic Rabbit(100339376) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • sheep(101121265) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Horse(100061914) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • dog(482131) gamma-aminobutyric acid (GABA) A receptor, alpha 2

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
(±)-Baclofen, ≥98% (HPLC), solid,
Especie
human, rat
Muscimol hydrobromide, ≥98% (HPLC), solid,
Especie
human
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Especie
human
Isoguvacine hydrochloride, solid,
Especie
human
Piperidine-4-sulfonic acid, ,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
5β-Pregnan-3α-ol-20-one, ,
Especie
Bromazepam, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Especie
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Especie
human
trans-Dehydroandrosterone, ≥99%,
Especie
human, rat

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
2-Pyrrolidinone, ≥99%,
Especie
2-Pyrrolidinone, 99%,
Especie
Muscimol, powder,
Especie
β-Naphthoflavone, ≥98%,
Especie
(+)-Bicuculline, ≥97.0% (TLC),
Especie

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GABRA2 antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
bovine, dog, horse, human, mouse, rabbit, rat
Aplicación
western blot
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S399-19,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 594 antibody produced in mouse, clone S399-19,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 488 antibody produced in mouse, clone S399-19,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Allophycocyanin antibody produced in mouse, clone S399-19,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Norharmane, crystalline,
Especie
human
Harmane, 98%,
Especie
human
Flavone, ≥99.0%,
Especie
human, rat, mouse
Chrysin, ≥96.5%,
Especie
human, mouse
NO-711 hydrochloride, ≥98% (HPLC),
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
Flumazenil, >99% (HPLC), solid,
Especie
rat, human

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
Etiocholan-3α-ol-17-one, ,
Especie
human, rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Gabra2,
Especie
mouse
MISSION® esiRNA, targeting human GABRA2,
Especie
human