Anti-IGF1R (Ab-1165/1166) antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Anti-CD221 antibody produced in rabbit, Anti-IGFIR antibody produced in rabbit, Anti-JTK13 antibody produced in rabbit, Anti-MGC142170 antibody produced in rabbit, Anti-insulin-like growth factor 1 receptor antibody produced in rabbit
Peptide sequence around aa. 1163-1167/1164-1168 (T-D-Y-Y-R-K), according to the protein IGF1R.
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Target description
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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Cellular and molecular neurobiology, 37(6), 985-993 (2016-10-09)
Time-dependent alterations in several biological processes of an organism may be characterized as aging. One of the effects of aging is the decline in cognitive functions. Dietary restriction (DR), an intervention where the consumption of food is lessened but without
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