IGF1R
insulin-like growth factor 1 receptor
Synonyms:
CD221, IGFIR, IGFR, JTK13
Species:
Human IGF1R (3480), Mouse Igf1r (16001), Rat Igf1r (25718), domestic guinea pig Igf1r (100734840), chicken IGF1R (395889), naked mole-rat Igf1r (101710224), Horse IGF1R (100055698), domestic cat IGF1R (100500937), cow IGF1R (281848), dog IGF1R (442951)
UniProtKB ID:
Gene ID:
- Human(3480) Summary: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]
- Mouse(16001) insulin-like growth factor I receptor
- Rat(25718) insulin-like growth factor 1 receptor
- domestic guinea pig(100734840) insulin-like growth factor 1 receptor
- chicken(395889) insulin-like growth factor 1 receptor
- naked mole-rat(101710224) insulin-like growth factor 1 receptor
- Horse(100055698) insulin-like growth factor 1 receptor
- domestic cat(100500937) insulin-like growth factor 1 receptor
- cow(281848) insulin-like growth factor 1 receptor
- dog(442951) insulin-like growth factor 1 receptor
- sheep(443002) insulin-like growth factor 1 receptor
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Custom Gene Products
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IGF-IR Antibody, clone JBW902, clone JBW902, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-IGF-IRα subunit Antibody, from chicken, purified by affinity chromatography,
Species Reactivity
human, rhesus macaque
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-IGF1R (Ab-1161) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-IGF1R (pTyr1165/pTyr1166) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
western blot
Anti-Insulin-like Growth Factor-1 Receptor Antibody, α-subunit, clone 24-31, clone 24-31, Chemicon®, from mouse,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
immunoprecipitation (IP)
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
IGF1R (960-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt, ≥98% (HPLC), lyophilized powder,
Species
human
Insulin-like Growth Factor-I Receptor human, ≥95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human
IGF-IR (δ1-958) Protein, active, 20 µg, Active, N-terminal His6-tagged, recombinant human IGF-IR residues 959-end, for use in Kinase Assays.,
Species
human
esiRNA
Small Molecule - Substrate
Product Number
Description
Species