Skip to Content
Merck
All Photos(5)

Documents

N0758

Sigma-Aldrich

Naphthol AS-D chloroacetate

esterase substrate, fluorogenic, ≥98% (TLC), powder

Synonym(s):

3-Hydroxy-2-naphthoic-o-toluidide chloroacetate

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C20H16ClNO3
CAS Number:
Molecular Weight:
353.80
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

product name

Naphthol AS-D chloroacetate, esterase substrate

Assay

≥98% (TLC)

form

powder

solubility

acetone: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cc1ccccc1NC(=O)c2cc3ccccc3cc2OC(=O)CCl

InChI

1S/C20H16ClNO3/c1-13-6-2-5-9-17(13)22-20(24)16-10-14-7-3-4-8-15(14)11-18(16)25-19(23)12-21/h2-11H,12H2,1H3,(H,22,24)

InChI key

FMVKYSCWHDVMGO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Naphthol AS-D chloroacetate has been in a substrate solution for naphthol-AS-D-chloroacetate-esterase (CIAE) staining.
Naphthol AS-D chloroacetate has been used as a component of the substrate solution for naphthol-AS-D-chloroacetate-esterase (CIAE) staining to detect:
  • the paraffin-embedded kidney tissues
  • polymorphonuclear (PMN) cells
  • endometrial tissues
  • neutrophils from mice small intestine

Substrates

Substrate for histochemical localization of esterases

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Ivonne Maciel Arciniega-Martínez et al.
Journal of neuroimmunology, 362, 577764-577764 (2021-11-26)
Muscarinic-acetylcholine-receptors (mAChRs) modulate intestinal homeostasis, but their role in inflammation is unclear; thus, this issue was the focus of this study. BALB/c mice were treated for 7 days with muscarine (mAChR/agonist), atropine (mAChR/antagonist) or saline. Small-intestine samples were collected for histology
Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury
Maekawa H, et al.
Cell Reports, 29(5), 1261-1273 (2019)
Hafez Sadeghi et al.
PloS one, 17(1), e0263409-e0263409 (2022-01-29)
The assessment of polymorphonuclear leukocyte (PMN) proportions (%) of endometrial samples is the hallmark for subclinical endometritis (SCE) diagnosis. Yet, a non-biased, automated diagnostic method for assessing PMN% in endometrial cytology slides has not been validated so far. We aimed
A novel cytologic sampling technique to diagnose subclinical endometritis and comparison of staining methods for endometrial cytology samples in dairy cows
Pascottini OB, et al.
Theriogenology, 84(8), 1438-1446 (2015)
Antonis Ioannou et al.
American journal of physiology. Gastrointestinal and liver physiology, 304(3), G283-G292 (2012-10-30)
Ischemia-reperfusion (IR) injury causes a vigorous immune response that is amplified by complement activation, leading to local and remote tissue damage. Using MRL/lpr mice, which are known to experience accelerated tissue damage after mesenteric IR injury, we sought to evaluate

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service