Skip to Content
Merck
All Photos(1)

Documents

E8250

Sigma-Aldrich

Esculin hydrate

≥98%

Synonym(s):

(-)-Esculin, 6,7-Dihydroxycoumarin 6-glucoside, Esculetin 6-β-D-glucoside

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C15H16O9 · xH2O
CAS Number:
Molecular Weight:
340.28 (anhydrous basis)
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥98%

SMILES string

O.OC[C@H]1O[C@@H](Oc2cc3C=CC(=O)Oc3cc2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C15H16O9.H2O/c16-5-10-12(19)13(20)14(21)15(24-10)23-9-3-6-1-2-11(18)22-8(6)4-7(9)17;/h1-4,10,12-17,19-21H,5H2;1H2/t10-,12-,13+,14-,15-;/m1./s1

InChI key

CQYPGSKIFJFVDQ-QWFKVUSTSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Esculin hydrate has vasoprotective and venotonic properties.

Application

Esculin hydrate has been used as a component of sporulation-inducing esculin agar. It has also been used for esculin uptake assay.

Biochem/physiol Actions

Esculin is a coumarin glycoside that demonstrates antioxidant activitites and protection against chemically-induced carcinogenesis. Esculin is utilized in microbiology for the isolation and identification of Enterococcus (group D streptococci).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Safety Properties and probiotic potential of Bacillus subtilis KATMIRA1933 and Bacillus amyloliquefaciens B-1895
AlGburi A, et al.
Advances in Microbiology, 6(6), 432-432 (2016)
The Clinician's Handbook of Natural Medicine (2015)
Safety Properties and probiotic potential of Bacillus subtilis KATMIRA1933 and Bacillus amyloliquefaciens B-1895
Ma QJ, et al.
Sci. Hortic., 220, 259-266 (2017)
S G Jenkins et al.
Journal of clinical microbiology, 49(11), 3947-3949 (2011-09-02)
A total of 142 stool specimens were evaluated for vancomycin-resistant enterococcus (VRE). Twenty-four-hour sensitivities and specificities, respectively, were 98% and 95% for Spectra VRE chromogenic agar (Remel, Lenexa, KS), 86% and 92% for bile esculin azide with vancomycin (BEAV; Remel)
Emiliano Ricardo Vasconcelos Rios et al.
Chemico-biological interactions, 188(1), 246-254 (2010-08-04)
This work describes the gastroprotective actions of esculin (6,7-dihydroxycoumarin-6-o-glucoside) against indomethacin- or ethanol-induced lesions and verifies the role of nitric oxide, ATP-dependent K(+) channels, prostaglandins, transient receptor potential vanilloid 1 and antioxidant effects in the gastroprotective mechanism of esculin in

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service