P5891

L-Pyroglutamic acid 2-naphthylamide

≥99% (TLC), suitable for ligand binding assays

• Synonym(s): L-Pyroglutamic acid β-naphthylamide, L-Pyrrolidonyl-β-naphthylamide, N¹-(2-Naphthyl)-L-pyroglutamic acid, PYR
• Empirical Formula (Hill Notation): C₁₅H₁₄N₂O₂
• CAS Number: 22155-91-5
• Molecular Weight: 254.28
• Beilstein: 5066652
• EC Number: 244-809-9
• MDL number: MFCD00055911
• UNSPSC Code: 12352209
• PubChem Substance ID: 329820238
• NACRES: NA.26

Properties

• product name: L-Pyroglutamic acid 2-naphthylamide, ≥99% (TLC)
• Assay: ≥99% (TLC)
• form: powder
• technique(s): ligand binding assay: suitable
• color: white to off-white
• storage temp.: 2-8°C
• SMILES string: O=C1CC[C@H](N1)C(=O)Nc2ccc3ccccc3c2
• InChI: 1S/C15H14N2O2/c18-14-8-7-13(17-14)15(19)16-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8H2,(H,16,19)(H,17,18)/t13-/m0/s1
• InChI key: BZEPQNMASTUAMY-ZDUSSCGKSA-N

Description

Application

A substrate for pyroglutamate aminopeptidase. Used for differentiation of Group A streptococci and enterococci from other streptococci.

Biochem/physiol Actions

Pyroglutamic acid is known to participate in the gamma-glutamyl cycle. Recent studies show that a congenital metabolic error was associated with increased pyroglutamic excretion in urine.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Pictograms: GHS09
• Signal Word: Warning
• Hazard Statements: H400
• Precautionary Statements: P273
• Hazard Classifications: Aquatic Acute 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves