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P6863

Sigma-Aldrich

PDAM

≥70% purity (HPLC), for HPLC derivatization, solid

Synonym(s):

1-Pyrenyldiazomethane, Pyrene, 1-(diazomethyl)

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About This Item

Empirical Formula (Hill Notation):
C17H10N2
CAS Number:
78377-23-8
Molecular Weight:
242.27
MDL number:
MFCD00467268
UNSPSC Code:
12171500
PubChem Substance ID:
329820256
NACRES:
MA.02

product name

PDAM, for HPLC derivatization

grade

for HPLC derivatization

Quality Level

200

Assay

≥70% (HPLC)

form

solid

λmax

338-344 nm

fluorescence

λem 371-379 nm

application(s)

diagnostic assay manufacturing
hematology
histology

shipped in

dry ice

storage temp.

−20°C

SMILES string

[N-]=[N+]=Cc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C17H10N2/c18-19-10-14-7-6-13-5-4-11-2-1-3-12-8-9-15(14)17(13)16(11)12/h1-10H

InChI key

PEIBAWRLFPGPAT-UHFFFAOYSA-N

Related Categories

Application

Fluorescent diazoalkane useful as an HPLC derivatization reagent for carboxylic acid detection with better detection limit parameters and greater chemical stability than the commonly used 9-anthryldiazomethane.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000360430
0000355054
0000360430
0000301834
0000355054

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Liquid chromatographic determination of biotin by using 1-pyrenyldiazomethane as a pre-column fluorescent labelling reagent.
T Yoshida et al.
Journal of chromatography, 456(2), 421-426 (1988-12-16)
G A Mills et al.
Journal of chromatography. B, Biomedical sciences and applications, 730(1), 113-122 (1999-08-07)
Short chain fatty acids (SFCAs) are nutritionally important products of colonic bacteria. Their analysis in faeces is problematic. We report a headspace solid-phase microextraction procedure in which faecal SCFAs are derivatised on the fibre in-situ with 1-pyrenyldiazomethane. With this method
O L Brekke et al.
Journal of lipid research, 38(9), 1913-1922 (1997-11-05)
A highly sensitive method to determine agonist-induced release of endogenous fatty acids from cells in culture was developed using high-performance liquid chromatography and fluorescence detection. Fatty acids were selectively derivatized with 1-pyrenyldiazomethane and separated on a LC18 reversed phase column
Qi Yang et al.
Journal of controlled release : official journal of the Controlled Release Society, 255, 73-80 (2017-04-02)
Tumor heterogeneity, which describes the genetically and phenotypically distinct subpopulations of tumor cells present within the same tumor or patient, presents a major challenge to targeted delivery of diagnostic and/or therapeutic agents. An ideal targeting strategy should deliver a given
F Iohan et al.
Journal of chromatography, 564(1), 27-41 (1991-03-08)
A new procedure is described for the detection of the acidic metabolites of cortisol (cortoic acids) as the pyrenylmethyl-21-oic esters. The derivatizing reagent, diazomethylpyrene, was prepared by an improved procedure. The reagent was used at room temperature, required no catalyst
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