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850464C

Avanti

18:0-14:0 PC

1-stearoyl-2-myristoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

1-octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine; SMPC; PC(18:0/14:0)

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About This Item

Empirical Formula (Hill Notation):
C40H80NO8P
CAS Number:
206640-20-2
Molecular Weight:
734.04
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850464C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850464C

concentration

10 mg/mL (850464C-25mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC) is a major bilayer-forming phospholipid in which the headgroup carries a positively and negatively charged quaternary amine and a phosphate, respectively.

Application

18:0-14:0 PC (1-stearoyl-2-myristoyl-sn-glycero-3-phosphocholine) may be used in liposomes to study its interference in the proliferation of several cell lines using transmission electron microscopy (TEM).

Biochem/physiol Actions

Phosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.

Packaging

5 mL Clear Glass Sealed Ampule (850464C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Anna Werlein et al.
Biochimica et biophysica acta, 1848(7), 1599-1608 (2015-04-29)
According to early experiments with natural extracts, phosphatidylcholines (PCs) are widely considered essentially non-toxic. In addition to these physiological mixed-chain PCs, many different synthetic diacyl-PCs are currently available, but they have never been systematically evaluated for any interference with cell
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features

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