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M1765

Sigma-Aldrich

1-Lauroyl-rac-glycerol

≥99%

Synonym(s):

1-Monododecanoyl-rac-glycerol, 1-Monolaurin, 1-Monolauroyl-rac-glycerol, rac-Glycerol 1-laurate, DL-α-Laurin

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About This Item

Linear Formula:
H3C(CH2)10COOCH2CH(OH)CH2OH
CAS Number:
142-18-7
Molecular Weight:
274.40
Beilstein:
1726740
EC Number:
205-526-6
MDL number:
MFCD00037815
UNSPSC Code:
12352211
PubChem Substance ID:
24896686
NACRES:
NA.25

biological source

plant

Assay

≥99%

form

powder

functional group

ketone

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCC(=O)OCC(O)CO

InChI

1S/C15H30O4/c1-2-3-4-5-6-7-8-9-10-11-15(18)19-13-14(17)12-16/h14,16-17H,2-13H2,1H3

InChI key

ARIWANIATODDMH-UHFFFAOYSA-N

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Related Categories

Biochem/physiol Actions

Monolaurin (1-Lauroyl-rac-glycerol) is used as an antimicrobial agent in various formulas and microemulsions and as a methane mitigation agent in ruminants.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Patrick M Schlievert et al.
Antimicrobial agents and chemotherapy, 52(12), 4448-4454 (2008-10-08)
Glycerol monolaurate (GML) is a fatty acid monoester that inhibits growth and exotoxin production of vaginal pathogens and cytokine production by vaginal epithelial cells. Because of these activities, and because of the importance of cytokine-mediated immune activation in human immunodeficiency
Amlan K Patra et al.
Phytochemistry, 71(11-12), 1198-1222 (2010-06-24)
Recently, greenhouse gas emissions have been of great concern globally. Ruminant livestock due to production of methane during normal fermentation in the rumen contributes substantially to the greenhouse effects. During the recent decade, a paradigm shift has been initiated whether
Kristi L Strandberg et al.
Antimicrobial agents and chemotherapy, 54(2), 597-601 (2009-12-17)
We investigated the effects of glycerol monolaurate (GML) on Lactobacillus, Candida, and Gardnerella vaginalis human vaginal microflora. Our previous work demonstrated that 6 months of GML treatment vaginally does not alter lactobacillus counts in monkeys. Candida and G. vaginalis are
H Shimada et al.
Journal of natural products, 60(4), 417-418 (1997-04-01)
Brine shrimp lethality-directed fractionation of the 95% EtOH extract of the powdered, dried berries of Serenoa repens (Bart.) Small (saw-palmetto) (Palmae) led to the isolation of two monoacylglycerides, 1-monolaurin (1) and 1-monomyristin (2). Compounds 1 and 2 showed moderate biological
Fenja Klevenhusen et al.
The British journal of nutrition, 102(9), 1308-1317 (2009-06-10)
Mitigation of methanogenesis in ruminants has been an important goal for several decades. Free lauric acid, known to suppress ruminal methanogenesis, has a low palatability; therefore, in the present study the aim was to evaluate the mitigation efficacy of its
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