BP1234

来曲唑

British Pharmacopoeia (BP) Reference Standard

• 别名: 4,4′-(1H-1,2,4-三唑-1-基亚甲基）双苄腈
• 经验公式（希尔记法）: C₁₇H₁₁N₅
• CAS号: 112809-51-5
• 分子量: 285.30
• MDL號碼: MFCD00866241
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• 品質等級: 100
• API 家族: letrozole
• 形狀: powder
• 儲存期限: limited shelf life, expiry date on the label
• 製造商／商標名: BP
• 應用: pharmaceutical; pharmaceutical small molecule
• 格式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: N#CC(C=C1)=CC=C1C(N2C=NC=N2)C3=CC=C(C#N)C=C3
• InChI: 1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
• InChI 密鑰: HPJKCIUCZWXJDR-UHFFFAOYSA-N
• 基因資訊: human ... CYP19A1(1588)

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Letrozole BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Letrozole Tablets

生化／生理作用

来曲唑是第三代非甾体芳香酶抑制剂。 它是芳香酶系统的竞争性抑制剂，因此可抑制雄激素向雌激素转化。来曲唑通过竞争性结合到该酶的细胞色素P450亚基的血红素上而抑制芳香酶，导致所有组织中雌激素的生物合成减少。

包裝

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H361fd,H373
• 防範說明: P202 - P260 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 2 - STOT RE 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable