Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
推荐产品
产品名称
Astec® CHIROBIOTIC® V2手性HPLC色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
物料
stainless steel column
Agency
suitable for USP L88
描述
HPLC column
产品线
Astec®
包装
pkg of 1 ea
制造商/商品名称
Astec®
参数
0-45 °C temperature
241 bar pressure (3500 psi)
技术
HPLC: suitable
LC/MS: suitable
长度 × 内径
25 cm × 4.6 mm
基质
High-purity silica gel particle platform
fully porous particle
基质活性基团
vancomycin phase
粒径
5 μm
孔径
200 Å
工作pH范围
3.5-7.0
分离技术
chiral
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一般描述
- 键合相：万古霉素
- 工作pH范围：3.5 - 7.0
- 粒径：5、10或16 μm
- 孔径：100Å（CHIROBIOTIC® V）或200Å（CHIROBIOTIC® V2）
CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献
应用
- Chiral analysis of dextromethorphan and levomethorphan in human hair by liquid chromatography-tandem mass spectrometry： 采用CHIROBIOTIC® V2色谱柱手性分离人体毛发中的右美沙芬和左美沙芬，说明柱子可在法医毒理学中用于准确的手性拆分(Ji et al., 2022)。
- Development and validation of an UFLC-MS/MS method for enantioselectivity determination of d,l-thero-methylphenidate, d,l-thero-ethylphenidate and d,l-thero-ritalinic acid in rat plasma： 在大鼠药动学研究中采用CHIROBIOTIC® V2色谱柱建立对映选择性测定方法，对药物开发和治疗监测有重要意义(Zhang et al., 2016)。
- New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase： 用CHIROBIOTIC® V2色谱柱开发新的HPLC方法分离华法林对映体，说明它的临床分析和治疗药物监测用处，体现生物医学研究应用的广泛性(Malakova et al., 2009)。
法律信息
应用
其他客户在看
实验方案
Efficient LC-MS separation of methamphetamine enantiomers in urine allows sensitive differentiation of illicit D-methamphetamine from over-the-counter L-methamphetamine.
Efficient LC-MS separation of methamphetamine enantiomers in urine allows sensitive differentiation of illicit D-methamphetamine from over-the-counter L-methamphetamine.
Efficient LC-MS separation of methamphetamine enantiomers in urine allows sensitive differentiation of illicit D-methamphetamine from over-the-counter L-methamphetamine.
Efficient LC-MS separation of methamphetamine enantiomers in urine allows sensitive differentiation of illicit D-methamphetamine from over-the-counter L-methamphetamine.
相关内容
Astec CHIROBIOTIC™ V2 Chiral HPLC Columns offered by Sigma-Aldrich. The polar organic and the polar ionic modes have become increasingly popular largely because of their ideal compatibility with MS detection and preparative LC.
Chromatograms
application for HPLCapplication for HPLCapplication for HPLCapplication for HPLC展开-
How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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What guard column should be used for the 15024AST column?
1 answer-
The recommended guard column for the 15024AST column is 15100AST, which is an Astec® CHIROBIOTIC® V2 Chiral HPLC Guard Column Cartridge with a 5 μm particle size and dimensions of 2 cm length and 4 mm inner diameter. Additionally, the recommended holder is 21150AST, a Supelguard™ Guard Cartridge Holder Stand-Alone (Swivel-type) designed for use with Supelguard cartridges, with dimensions of 2 cm length and 2 to 4.6 mm inner diameter.
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