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Merck
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主要文件

T9924

Sigma-Aldrich

肌钙蛋白I 来源于人类心脏

lyophilized powder

别名:

Tn-I

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About This Item

CAS号:
77108-40-8
MDL编号:
MFCD00213059
UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human heart

质量水平

200

表单

lyophilized powder

纯化方式

affinity chromatography

技术

inhibition assay: suitable

溶解性

water: 5 vial/mL, clear, colorless

UniProt登记号

P19429

运输

dry ice

储存温度

−20°C

基因信息

human ... TNNI3(7137)

应用

来源于人类心脏的肌钙蛋白I可用于是否肌动蛋白和醛缩酶可防止兔肌肉乳酸脱氢酶被抗坏血酸抑制的研究。

生化/生理作用

肌钙蛋白I可与原肌球蛋白相互作用，并以钙依赖性方式调节横纹肌的收缩。此外，肌钙蛋白I还可抑制肌动蛋白ATP酶，并可作为体内和体外血管生成，以及体内肿瘤转移的选择性和有效抑制剂。
肌钙蛋白的抑制亚基，负责抑制肌动蛋白-肌球蛋白的结合以及ATP酶活性。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCL9140
SLCK8914
SLCK2148
SLCF6316
SLCD8854

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Nikita Sitkov et al.
Micromachines, 12(6) (2021-07-03)
The problems of chronic or noncommunicable diseases (NCD) that now kill around 40 million people each year require multiparametric combinatorial diagnostics for the selection of effective treatment tactics. This could be implemented using the biosensor principle based on peptide aptamers
M A Moses et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(6), 2645-2650 (1999-03-17)
Cartilage is an avascular and relatively tumor-resistant tissue. Work from a number of laboratories, including our own, has demonstrated that cartilage is an enriched source of endogenous inhibitors of angiogenesis. In the course of a study designed to identify novel
Percy J Russell et al.
Journal of enzyme inhibition and medicinal chemistry, 19(1), 91-98 (2004-06-19)
Muscle-type LDH (LDH-m4) activity is critical for efficient anaerobic glycolysis. The results here show that rabbit LDH-M4 is inhibited by concentrations of ascorbate normally found in tissues. Aldolase and muscle G-actin were found to protect and to reverse inhibitions of

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