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Merck
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Key Documents

T0175

Sigma-Aldrich

Troponin T from human heart

≥60% (SDS-PAGE), lyophilized powder

别名:

Tn-T

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About This Item

CAS号:
150901-75-0
MDL號碼:
MFCD00213049
分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human heart

品質等級

200

形狀

lyophilized powder

純化經由

affinity chromatography

濃度

≥60% (SDS-PAGE)

技術

ELISA: suitable

溶解度

10 mM HCl: 500 μg/mL, clear, colorless

UniProt登錄號

P45379

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

human ... TNNT2(7139)

一般說明

The cardiac troponin T gene (TNNT2) is located on human chromosome 1 and spans around 17kb. It codes for a 288-amino-acid peptide of 36−39kDa.

應用

Troponin T from human heart has been used in competitive enzyme-linked immunosorbent assay (ELISA) for the quantification of troponin T (TnT).

生化／生理作用

The tropomyosin-binding subunit of troponin. The cardiac troponin T gene (TNNT2) helps to connect the troponin complex to α-tropomyosin, thereby participates in the modulation of contractile function.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Inherited cardiomyopathies
Emery and Rimoin's Principles and Practice of Medical Genetics, 1-38 (2013)
A skeletal muscle troponin T specific ELISA based on the use of an antibody against the soluble troponin T (16-31) fragment
Tsitsilonis O E, et al.
Journal of Immunological Methods, 268(2), 141-148 (2002)
Nikita Sitkov et al.
Micromachines, 12(6) (2021-07-03)
The problems of chronic or noncommunicable diseases (NCD) that now kill around 40 million people each year require multiparametric combinatorial diagnostics for the selection of effective treatment tactics. This could be implemented using the biosensor principle based on peptide aptamers

商品

Troponin

Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds to actin

Troponin

Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds to actin

Troponin

Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds to actin

Troponin

Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds to actin

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