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Merck
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文件

T0665

Sigma-Aldrich

全转铁蛋白 人

powder, BioReagent, suitable for cell culture, ≥97%

别名:

嗜铁蛋白，铁饱和

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About This Item

CAS号:
11096-37-0
EC號碼:
234-318-8
MDL號碼:
MFCD00131337
分類程式碼代碼:
12352202
NACRES:
NA.75

生物源

human plasma

描述

Iron-saturated

產品線

BioReagent

化驗

≥97%

形狀

powder

技術

cell culture | mammalian: suitable

雜質

HIV, HBsAg and HCV, none detected (tested by FDA approved testing methods)
 endotoxin, tested

溶解度

H2O: 50 mg/mL

UniProt登錄號

P02787

運輸包裝

ambient

儲存溫度

2-8°C

基因資訊

human ... TF(7018)

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應用

罗斯韦尔公园纪念研究所（Roswell Park Memorial Institute (RPMI)）已通过补充人全转铁蛋白进行原红细胞增殖测定，同时这种成分还被补充进培养基，以进行电感耦合等离子体发射光谱分析。
转铁蛋白是一种存在于血清中的主要铁结合和细胞传递分子。 无血清细胞培养系统需要一种铁的传递形式。 转铁蛋白是铁的优选传递形式，因为细胞可通过细胞表面上的转铁蛋白受体以生理学上适当的方式对转铁蛋白结合的铁进行处理。 人全转铁蛋白是一种高亲和性的转铁蛋白，可与多种细胞类型一起使用。 人全转铁蛋白在使用前会加载铁并可被直接添加到贫铁或无铁的细胞培养基中。

生化／生理作用

以一种生理性稳定且安全的形式向细胞提供铁。

準備報告

在60 °C（最低）经至少10小时的热处理。

分析報告

经琼脂糖凝胶电泳纯度。
通过ICP的铁含量是按批次进行报道的。

免責聲明

供研究使用。在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

分析证书(COA)

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Jill M Brown et al.
Nature communications, 9(1), 3849-3849 (2018-09-23)
Self-interacting chromatin domains encompass genes and their cis-regulatory elements; however, the three-dimensional form a domain takes, whether this relies on enhancer-promoter interactions, and the processes necessary to mediate the formation and maintenance of such domains, remain unclear. To examine these
Co-operative signalling mechanisms required for erythroid precursor expansion in response to erythropoietin and stem cell factor
Arcasoy O and Jiang X
British Journal of Haematology, 130(1), 121-129 (2005)
Engineered mitochondrial ferritin as a magnetic resonance imaging reporter in mouse olfactory epithelium
Iordanova B, et al.
Testing, 8(8), e72720-e72720 (2013)
Senthil Raja Jayapal et al.
Cell cycle (Georgetown, Tex.), 15(22), 3070-3081 (2016-09-23)
Cyclin A2 is an essential gene for development and in haematopoietic stem cells and therefore its functions in definitive erythropoiesis have not been investigated. We have ablated cyclin A2 in committed erythroid progenitors in vivo using erythropoietin receptor promoter-driven Cre
Marcella Brescia et al.
Cells, 9(4) (2020-04-08)
Duchenne muscular dystrophy (DMD) is a fatal X-linked muscle wasting disorder arising from mutations in the ~2.4 Mb dystrophin-encoding DMD gene. RNA-guided CRISPR-Cas9 nucleases (RGNs) are opening new DMD therapeutic routes whose bottlenecks include delivering sizable RGN complexes for assessing
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Discover our primary human hepatocytes and plating and maintenance media formulations. Explore our protocol for plateable primary hepatocyte cell culture.

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