SRP8059

Jagged-2 (human): FC (human)

recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)

• 别名: Alpha-ketoglutarate-dependent dioxygenase FTO, Protein jagged-2, hJ2
• 分類程式碼代碼: 12352200
• NACRES: NA.32

属性

• 重組細胞: expressed in HEK 293 cells
• 化驗: ≥90% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: ~150 kDa by SDS-PAGE
• 雜質: <0.1 EU/μgtested
• UniProt登錄號: Q9Y219
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... JAG2(3714)

说明

一般說明

Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.

序列

Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.

外觀

Lyophilized. Contains PBS + 0.02 % CHAPS.

重構

Reconstitute with 100μl sterile water.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable