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Merck
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SML2669

Sigma-Aldrich

ITK7

≥98% (HPLC)

别名:

8-methyl-7-(prop-1-yn-1-yl)-2-((pyrimidin-2-ylthio)methyl)quinazolin-4(3H)-one

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About This Item

经验公式（希尔记法）:
C17H14N4OS
CAS号:
2411890-36-1
分子量:
322.38
UNSPSC代码:
12352200
NACRES:
NA.77

方案

≥98% (HPLC)

表单

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

2-8°C

SMILES字符串

CC1=C(N=C(CSC2=NC=CC=N2)NC3=O)C3=CC=C1C#CC

生化/生理作用

ITK7 is a cell penetrant, potent and selective inhibitor of PARP11 mono-ADP-ribosylation (MARylation) activity.
cell penetrant, potent and selective inhibitor of PARP11 mono-ADP-ribosylation

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ilsa T Kirby et al.
Cell chemical biology, 25(12), 1547-1553 (2018-10-23)
Poly-ADP-ribose polymerases (PARPs1-16) play pivotal roles in diverse cellular processes. PARPs that catalyze poly-ADP-ribosylation (PARylation) are the best characterized PARP family members because of the availability of potent and selective inhibitors for these PARPs. There has been comparatively little success in

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