SML1452

Ibufenac

≥95% (HPLC)

• 别名: 4-(2-Methylpropyl)-benzeneacetic acid, 4-Isobutylphenylacetic acid
• 经验公式（希尔记法）: C₁₂H₁₆O₂
• CAS号: 1553-60-2
• 分子量: 192.25
• EC號碼: 216-302-2
• MDL號碼: MFCD00864374
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825891
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: −20°C
• SMILES 字串: OC(CC1=CC=C(CC(C)C)C=C1)=O
• InChI: 1S/C12H16O2/c1-9(2)7-10-3-5-11(6-4-10)8-12(13)14/h3-6,9H,7-8H2,1-2H3,(H,13,14)
• InChI 密鑰: CYWFCPPBTWOZSF-UHFFFAOYSA-N
• 基因資訊: human ... PTGS1(5742) , PTGS2(5743)

说明

生化／生理作用

Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-1 and -2 activity with IC50 values of 17.4 and 13.1 μM, respectively and > 40 μM for 5-LOX. It has been used in studies of drug-induced hepatotoxicity.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable