SML1236

(-)-尼古丁 酒石酸氢盐

≥98% (HPLC)

• 别名: (-)-1-甲基-2-(3-吡啶基)吡咯烷 (+)-酒石酸氢盐
• 经验公式（希尔记法）: C₁₀H₁₄N₂ · 2C₄H₆O₆
• CAS号: 65-31-6
• 分子量: 462.41
• EC號碼: 200-607-2
• 分類程式碼代碼: 12352210
• PubChem物質ID: 329825736
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D +20 to +26°, c = 1.0 in water
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: H₂O: 20 mg/mL, clear
• 儲存溫度: room temp
• SMILES 字串: CN1CCC[C@H]1C2=CC=CN=C2.C
• InChI: 1S/C10H14N2.CH4/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;/h2,4,6,8,10H,3,5,7H2,1H3;1H4/t10-;/m0./s1
• InChI 密鑰: RYYKFQGHMYGLEL-PPHPATTJSA-N

说明

應用

(−)-Nicotine hydrogen tartrate salt has been used as an agonist for acetylcholine receptor (AChr).

(−)-Nicotine hydrogen tartrate salt has been used in intracellular calcium imaging.

生化／生理作用

NHT is considered to be more stable than nicotine. Nicotine is highly addictive drug and is indirectly but strongly associated with tobacco related diseases. It helps to discontinue smoking. Nicotine might serve as a therapeutic agent in treating Alzheimer’s disease, Parkinson’s disease and ulcerative colitis.

原型烟酸乙酰胆碱受体激动剂;天然异构体。

安全信息

• 象形圖: GHS06,GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H301,H319,H330,H361d,H411
• 防範說明: P202 - P260 - P264 - P273 - P304 + P340 + P310 - P305 + P351 + P338
• 危險分類: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2
• 儲存類別代碼: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 289.8 °F
• 閃點（°C）: 143.2 °C