推荐产品
化驗
≥95% (HPLC)
形狀
powder
顏色
white to light brown
溶解度
DMSO: 0.5 mg/mL, clear (warmed)
儲存溫度
−20°C
SMILES 字串
O=C1C2=C(CCS2)N=C(SCC(NC3=NC(C=CC(C)=C4)=C4S3)=O)N1C5=C(OC)C=CC=C5
InChI
1S/C23H20N4O3S3/c1-13-7-8-14-18(11-13)33-22(24-14)26-19(28)12-32-23-25-15-9-10-31-20(15)21(29)27(23)16-5-3-4-6-17(16)30-2/h3-8,11H,9-10,12H2,1-2H3,(H,24,26,28)
InChI 密鑰
RHUJMHOIQBDFQR-UHFFFAOYSA-N
生化／生理作用
IWP-4 是 Wnt 通路调节蛋白 Porupine（Porcn）的有效抑制剂。 IWP-4 阻断棕榈酸酯化以及随后的 Wnt 分泌和活性。 IWP-4 诱导人多能干细胞分化为心肌细胞。
IWP-4 阻断 Wnt 家族成员 5a。它阻断 Wnt 蛋白分泌，并阻断经典和非经典信号通路。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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Here we provide a protocol for the directed differentiation of hEPI-NCSC into midbrain dopaminergic neurons, which degenerate in Parkinson's disease. hEPI-NCSC are neural crest-derived multipotent stem cells that persist into adulthood in the bulge of hair follicles. The experimental design
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Over the last decade, Organ-on-Chip (OoC) emerged as a promising technology for advanced in vitro models, recapitulating key physiological cues. OoC approaches tailored for cardiac tissue engineering resulted in a variety of platforms, some of which integrate stimulation or probing
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