SML0473

Noladin ether

≥98% (HPLC)

• 别名: 2-Arachidonylglyceryl ether, 2-[(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraen-1-yloxy]-1,3-propanediol; 2-AG ether, HU 310
• 经验公式（希尔记法）: C₂₃H₄₀O₃
• CAS号: 222723-55-9
• 分子量: 364.56
• EC 号: 200-578-6
• UNSPSC代码: 12352200
• NACRES: NA.77

属性

• 方案: ≥98% (HPLC)
• 表单: solution
• 药品控制: regulated under CDSA - not available from Sigma-Aldrich Canada
• 浓度: 10 mg/mL in ethanol (1% w/v)
• 颜色: colorless to light yellow
• 运输: dry ice
• 储存温度: −70°C
• SMILES字符串: O(C(CO)CO)CCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC
• InChI: 1S/C23H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26-23(21-24)22-25/h6-7,9-10,12-13,15-16,23-25H,2-5,8,11,14,17-22H2,1H3/b7-6-,10-9-,13-12-,16-15-
• InChI key: CUJUUWXZAQHCNC-DOFZRALJSA-N

说明

生化/生理作用

Noladin ether (2-Arachidonyl glycerol ether) is a CB1 agonist.

Noladin ether (2-Arachidonyl glycerol ether) is a stable analog of the endogenous cannabanoid 2-Arachidonylglycerol (2-AG) with selectivity for CB1 receptors. Noladin ether is a CB1 agonist. The Ki values for CB1 vs CB2 receptors are 21.2 nM and 3 mM, respectively. Noladin ether induces sedation and has modest antinociceptive activity in vivo, and reduces inter ocular pressure after administration in the eye.

安全信息

• 象形图: GHS02,GHS07
• 警示用语：: Danger
• 危险声明: H225,H319
• 预防措施声明: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• 危险分类: Eye Irrit. 2 - Flam. Liq. 2
• 储存分类代码: 3 - Flammable liquids
• WGK: WGK 2
• 闪点(°F): 57.2 °F - closed cup
• 闪点(°C): 14.0 °C - closed cup