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Merck

SML0180

Sigma-Aldrich

乙酰甲啶 盐酸盐

≥98% (HPLC)

别名:

1-Azabicyclo[2.2.2]oct-3-yl acetate hydrochloride, 3-Acetoxyquinuclidine hydrochloride

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About This Item

经验公式(希尔记法):
C9H15NO2 · HCl
CAS号:
分子量:
205.68
EC號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

white to tan

溶解度

H2O: ≥15 mg/mL at ~60 °C

儲存溫度

−20°C

SMILES 字串

Cl.CC(=O)O[C@H]1CN2CC[C@H]1CC2

InChI

1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H/t9-;/m0./s1

InChI 密鑰

LWWSARSTZGNKGV-FVGYRXGTSA-N

應用

Aceclidine hydrochloride may be used in muscarinic acetylcholine receptor-mediated cell signaling studies.

生化/生理作用

Aceclidine at a concentration of 5 and 50 μg is capable of enhancing the outflow facility, following ciliary muscle disinsertion.
Aceclidine hydrochloride is a parasympathomimetic drug with weak anticholinesterase activity. It acts on cholinergic nerve-endings, lowers intraocular pressure and potent therapeutic agent for open-angle glaucoma.
Aceclidine is a non-selective muscarinic acetylcholine receptor partial agonist that is effective in reducing intraocular pressure.

特點和優勢

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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Aceclidine effects on outflow facility after ciliary muscle disinsertion
Hubbard WC, et al.
Ophthalmologica, 210(5), 303-307 (1996)
Double-blind cross-over comparison of aceclidine and pilocarpine in open-angle glaucoma.
J H Romano
The British journal of ophthalmology, 54(8), 510-521 (1970-08-01)

商品

Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.

Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.

Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.

Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.

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