SML0081

Zacopride hydrochloride hydrate

≥98% (HPLC)

• 别名: 4-Amino-N-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride hydrate
• 经验公式（希尔记法）: C₁₅H₂₀ClN₃O₂ · HCl · xH₂O
• CAS号: 101303-98-4
• 分子量: 346.25 (anhydrous basis)
• MDL號碼: MFCD20488057
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825143
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to tan
• 溶解度: H₂O: ≥10 mg/mL
• 起源: Wyeth
• 儲存溫度: 2-8°C
• SMILES 字串: O.Cl.COc1cc(N)c(Cl)cc1C(=O)NC2CN3CC[C@H]2CC3
• InChI: 1S/C15H20ClN3O2.ClH.H2O/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19;;/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20);1H;1H2
• InChI 密鑰: NPXXKMBXEODDAF-UHFFFAOYSA-N

说明

生化／生理作用

Zacopride is a sub-nanomolar antagonist of the serotonin 5-HT3 receptor that also displays agonist-like activity against 5-HT4 receptors. It is a potent anxiolytic in animal models, and also has strong antiemetic effects, and also increases aldosterone levels via activation of 5-HT4 receptor in the adrenal glands.

特點和優勢

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable