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Merck
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Key Documents

SAB5702269

Sigma-Aldrich

Anti-CD68 Antibody, clone 5S2F7, Rabbit Monoclonal

别名:

CD68,GP110,LAMP4,SCARD1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

5S2F7, monoclonal

形狀

liquid

分子量

80-130 kDa

物種活性

human, rat, rat

濃度

1 mg/mL

技術

flow cytometry: 1:50 - 1:200
western blot: 1:500 - 1:1000

顏色

colorless

同型

IgG

免疫原序列

TSQGPSTATHSPATTSHGNATVHPTSNSTATSPGFTSSAHPEPPPPSPSPSPTSKETIGDYTWTNGSQPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNK

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CD68(968)

一般說明

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD68 (NP_001242.2).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

應用

WB, FC

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險聲明

危險分類

Aquatic Chronic 2 - Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3


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