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Merck
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Key Documents

SAB5201536

Sigma-Aldrich

Monoclonal Anti-Qki (Pan) antibody produced in mouse

clone S147-6, purified immunoglobulin

别名:

Anti-Hqk, Anti-KH Domain Containing, Anti-Protein quaking

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

S147-6, monoclonal

形狀

buffered aqueous solution

分子量

antigen predicted mol wt 36-38 kDa

物種活性

human, rat, mouse

濃度

1 mg/mL

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

同型

IgG2b

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... QKI(9444)

免疫原

Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical). Rat: 99% identity (339/341 amino acids identical) >90% identity with QKI-6, QKI-7 and QKI-7b.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

PBS pH 7.4, 50% glycerol, 0.1% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Xin Zhou et al.
The Journal of clinical investigation, 130(5), 2220-2236 (2020-03-24)
Lipid-rich myelin forms electrically insulating, axon-wrapping multilayers that are essential for neural function, and mature myelin is traditionally considered metabolically inert. Surprisingly, we discovered that mature myelin lipids undergo rapid turnover, and quaking (Qki) is a major regulator of myelin
Xin Zhou et al.
eLife, 10 (2021-05-05)
Myelination depends on timely, precise control of oligodendrocyte differentiation and myelinogenesis. Cholesterol is the most abundant component of myelin and essential for myelin membrane assembly in the central nervous system. However, the underlying mechanisms of precise control of cholesterol biosynthesis

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